LINC complexes promote homologous recombination in part through inhibition of nonhomologous end joining.

Lawrence, Katherine S; Tapley, Erin C; Cruz, Victor E; Li, Qianyan; Aung, Kayla; Hart, Kevin C; Schwartz, Thomas U; Starr, Daniel A; Engebrecht, JoAnne

Lawrence, Katherine S; Tapley, Erin C; Cruz, Victor E; Li, Qianyan; Aung, Kayla; Hart, Kevin C; Schwartz, Thomas U; Starr, Daniel A; Engebrecht, JoAnne.

Affiliation

Lawrence KS; Department of Molecular and Cellular Biology; Biochemistry, Molecular Cellular, and Developmental Biology Graduate Group, University of California, Davis, Davis, CA 95616.
Tapley EC; Department of Molecular and Cellular Biology; Biochemistry, Molecular Cellular, and Developmental Biology Graduate Group, University of California, Davis, Davis, CA 95616.
Cruz VE; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139.
Li Q; Department of Molecular and Cellular Biology; Biochemistry, Molecular Cellular, and Developmental Biology Graduate Group, University of California, Davis, Davis, CA 95616.
Aung K; Department of Molecular and Cellular Biology; Biochemistry, Molecular Cellular, and Developmental Biology Graduate Group, University of California, Davis, Davis, CA 95616.
Hart KC; Department of Molecular and Cellular Biology; Biochemistry, Molecular Cellular, and Developmental Biology Graduate Group, University of California, Davis, Davis, CA 95616.
Schwartz TU; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139.
Starr DA; Department of Molecular and Cellular Biology; Biochemistry, Molecular Cellular, and Developmental Biology Graduate Group, University of California, Davis, Davis, CA 95616 jengebrecht@ucdavis.edu dastarr@ucdavis.edu.
Engebrecht J; Department of Molecular and Cellular Biology; Biochemistry, Molecular Cellular, and Developmental Biology Graduate Group, University of California, Davis, Davis, CA 95616 jengebrecht@ucdavis.edu dastarr@ucdavis.edu.

J Cell Biol ; 215(6): 801-821, 2016 Dec 19.

Article in En | MEDLINE | ID: mdl-27956467

Subject(s)

Caenorhabditis elegans Proteins/metabolism; DNA End-Joining Repair; Homologous Recombination; Multiprotein Complexes/metabolism; Cell Cycle Checkpoints/drug effects; Cell Cycle Checkpoints/radiation effects; Cell Nucleus/drug effects; Cell Nucleus/metabolism; Cell Nucleus/radiation effects; Cell Proliferation/drug effects; Cell Proliferation/radiation effects; Cisplatin/pharmacology; Cross-Linking Reagents/metabolism; DNA Damage; DNA End-Joining Repair/drug effects; DNA End-Joining Repair/radiation effects; Germ Cells/cytology; Germ Cells/drug effects; Germ Cells/metabolism; Germ Cells/radiation effects; Homologous Recombination/drug effects; Homologous Recombination/radiation effects; Humans; Hydroxyurea/pharmacology; Meiosis/drug effects; Meiosis/radiation effects; Membrane Proteins/metabolism; Microtubule-Associated Proteins/metabolism; Microtubules/drug effects; Microtubules/metabolism; Microtubules/radiation effects; Models, Biological; Nuclear Proteins/metabolism; Polymerization/drug effects; Protein Binding/drug effects; Protein Binding/radiation effects; Protein Transport/drug effects; Protein Transport/radiation effects; Radiation, Ionizing

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Caenorhabditis elegans Proteins / Multiprotein Complexes / DNA End-Joining Repair / Homologous Recombination Language: En Journal: J Cell Biol Year: 2016 Document type: Article Country of publication: United States

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