Hepatitis C Virus Infection of Cultured Human Hepatoma Cells Causes Apoptosis and Pyroptosis in Both Infected and Bystander Cells.

Kofahi, H M; Taylor, N G A; Hirasawa, K; Grant, M D; Russell, R S

Kofahi, H M; Taylor, N G A; Hirasawa, K; Grant, M D; Russell, R S.

Affiliation

Kofahi HM; Division of Biomedical Sciences, Faculty of Medicine, Memorial University, St. John's, Newfoundland A1B 3V6, Canada.
Taylor NG; Division of Biomedical Sciences, Faculty of Medicine, Memorial University, St. John's, Newfoundland A1B 3V6, Canada.
Hirasawa K; Division of Biomedical Sciences, Faculty of Medicine, Memorial University, St. John's, Newfoundland A1B 3V6, Canada.
Grant MD; Division of Biomedical Sciences, Faculty of Medicine, Memorial University, St. John's, Newfoundland A1B 3V6, Canada.
Russell RS; Division of Biomedical Sciences, Faculty of Medicine, Memorial University, St. John's, Newfoundland A1B 3V6, Canada.

Sci Rep ; 6: 37433, 2016 12 15.

Article in En | MEDLINE | ID: mdl-27974850

Subject(s)

Apoptosis/genetics; Bystander Effect; Hepacivirus/growth & development; Hepatocytes/virology; Host-Pathogen Interactions; Pyroptosis/genetics; Caspase 1/genetics; Caspase 1/metabolism; Caspase 3/genetics; Caspase 3/metabolism; Cell Line, Tumor; Cell Proliferation; Coculture Techniques; Gene Expression Regulation; Hepacivirus/pathogenicity; Hepatocytes/metabolism; Humans; Inflammasomes/metabolism; NLR Family, Pyrin Domain-Containing 3 Protein/genetics; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism; Signal Transduction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Apoptosis / Hepacivirus / Hepatocytes / Bystander Effect / Host-Pathogen Interactions / Pyroptosis Type of study: Etiology_studies Limits: Humans Language: En Journal: Sci Rep Year: 2016 Document type: Article Affiliation country: Canada Country of publication: United kingdom

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