Lycium barbarum polysaccharides inhibit proliferation and migration of bladder cancer cell lines BIU87 by suppressing Pi3K/AKT pathway.

Zhang, Xian-Jun; Yu, Hong-Yuan; Cai, Yong-Jian; Ke, Mang

Zhang, Xian-Jun; Yu, Hong-Yuan; Cai, Yong-Jian; Ke, Mang.

Affiliation

Zhang XJ; Department of Urology, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai, Zhejiang Province, PR China.
Yu HY; Department of Urology, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai, Zhejiang Province, PR China.
Cai YJ; Department of Urology, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai, Zhejiang Province, PR China.
Ke M; Department of Urology, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai, Zhejiang Province, PR China.

Oncotarget ; 8(4): 5936-5942, 2017 Jan 24.

Article in En | MEDLINE | ID: mdl-27992374

Subject(s)

Down-Regulation; Drugs, Chinese Herbal/pharmacology; Phosphatidylinositol 3-Kinases/metabolism; Proto-Oncogene Proteins c-akt/metabolism; Cell Line, Tumor; Cell Movement/drug effects; Cell Proliferation/drug effects; Chromones/pharmacology; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic/drug effects; Humans; Morpholines/pharmacology; Signal Transduction/drug effects; Urinary Bladder Neoplasms

Key words

Pi3K/AKT; bladder cancer; lycium barbarum polysaccharides; migration; proliferation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drugs, Chinese Herbal / Down-Regulation / Phosphatidylinositol 3-Kinases / Proto-Oncogene Proteins c-akt Limits: Humans Language: En Journal: Oncotarget Year: 2017 Document type: Article Country of publication: United States

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