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Carbon-11 and Fluorine-18 Radiolabeled Pyridopyrazinone Derivatives for Positron Emission Tomography (PET) Imaging of Phosphodiesterase-5 (PDE5).
Chekol, Rufael; Gheysens, Olivier; Ahamed, Muneer; Cleynhens, Jan; Pokreisz, Peter; Vanhoof, Greet; Janssens, Stefan; Verbruggen, Alfons; Bormans, Guy.
Affiliation
  • Chekol R; Laboratory of Radiopharmacy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven , BE-3000 Leuven, Belgium.
  • Gheysens O; Department of Imaging and Pathology, KU Leuven , and Nuclear Medicine, UZ Leuven, BE-300 Leuven Belgium.
  • Ahamed M; Laboratory of Radiopharmacy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven , BE-3000 Leuven, Belgium.
  • Cleynhens J; Laboratory of Radiopharmacy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven , BE-3000 Leuven, Belgium.
  • Pokreisz P; Department of Cardiovascular Sciences, UZ Leuven, KU Leuven , 3000 Leuven, Belgium.
  • Vanhoof G; Discovery Sciences, Janssen Pharmaceutica, R&D , B-2340 Beerse, Belgium.
  • Janssens S; Department of Cardiovascular Sciences, UZ Leuven, KU Leuven , 3000 Leuven, Belgium.
  • Verbruggen A; Laboratory of Radiopharmacy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven , BE-3000 Leuven, Belgium.
  • Bormans G; Laboratory of Radiopharmacy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven , BE-3000 Leuven, Belgium.
J Med Chem ; 60(1): 486-496, 2017 01 12.
Article in En | MEDLINE | ID: mdl-28009175
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carbon Radioisotopes / Fluorine Radioisotopes / Cyclic Nucleotide Phosphodiesterases, Type 5 Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2017 Document type: Article Affiliation country: Belgium Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carbon Radioisotopes / Fluorine Radioisotopes / Cyclic Nucleotide Phosphodiesterases, Type 5 Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2017 Document type: Article Affiliation country: Belgium Country of publication: United States