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Enhanced targeting of CML stem and progenitor cells by inhibition of porcupine acyltransferase in combination with TKI.
Agarwal, Puneet; Zhang, Bin; Ho, Yinwei; Cook, Amy; Li, Ling; Mikhail, Fady M; Wang, Youzhen; McLaughlin, Margaret E; Bhatia, Ravi.
Affiliation
  • Agarwal P; Division of Hematology and Oncology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL.
  • Zhang B; Division of Hematopoietic Stem Cell and Leukemia Research, City of Hope National Medical Center, Duarte, CA.
  • Ho Y; Division of Hematopoietic Stem Cell and Leukemia Research, City of Hope National Medical Center, Duarte, CA.
  • Cook A; Division of Hematopoietic Stem Cell and Leukemia Research, City of Hope National Medical Center, Duarte, CA.
  • Li L; Division of Hematopoietic Stem Cell and Leukemia Research, City of Hope National Medical Center, Duarte, CA.
  • Mikhail FM; Department of Genetics, University of Alabama at Birmingham, Birmingham, AL; and.
  • Wang Y; Oncology Disease Area, Novartis Institute of Biomedical Research, Cambridge, MA.
  • McLaughlin ME; Oncology Disease Area, Novartis Institute of Biomedical Research, Cambridge, MA.
  • Bhatia R; Division of Hematology and Oncology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL.
Blood ; 129(8): 1008-1020, 2017 02 23.
Article in En | MEDLINE | ID: mdl-28011678
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neoplastic Stem Cells / Protein-Tyrosine Kinases / Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Cell Proliferation / Enzyme Inhibitors / Membrane Proteins / Antineoplastic Agents Limits: Animals / Humans Language: En Journal: Blood Year: 2017 Document type: Article Affiliation country: Albania Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neoplastic Stem Cells / Protein-Tyrosine Kinases / Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Cell Proliferation / Enzyme Inhibitors / Membrane Proteins / Antineoplastic Agents Limits: Animals / Humans Language: En Journal: Blood Year: 2017 Document type: Article Affiliation country: Albania Country of publication: United States