Transforming Growth Factor-ß<sub>1</sub> Modulates the Expression of Syndecan-4 in Cultured Vascular Endothelial Cells in a Biphasic Manner.

Hara, Takato; Yoshida, Eiko; Fujiwara, Yasuyuki; Yamamoto, Chika; Kaji, Toshiyuki

Transforming Growth Factor-ß₁ Modulates the Expression of Syndecan-4 in Cultured Vascular Endothelial Cells in a Biphasic Manner.

Hara, Takato; Yoshida, Eiko; Fujiwara, Yasuyuki; Yamamoto, Chika; Kaji, Toshiyuki.

Affiliation

Hara T; Faculty of Pharmaceutical Sciences, Department of Environmental Health, Tokyo University of Science, Noda 278-8510, Japan.
Yoshida E; Faculty of Pharmaceutical Sciences, Department of Environmental Health, Tokyo University of Science, Noda 278-8510, Japan.
Fujiwara Y; Department of Environmental Health, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Hachioji 192-0392, Japan.
Yamamoto C; Faculty of Pharmaceutical Sciences, Department of Environmental Health, Toho University, Funabashi 274-8510, Japan.
Kaji T; Faculty of Pharmaceutical Sciences, Department of Environmental Health, Tokyo University of Science, Noda 278-8510, Japan.

J Cell Biochem ; 118(8): 2009-2017, 2017 08.

Article in En | MEDLINE | ID: mdl-28019669

Subject(s)

Endothelial Cells/drug effects; Smad2 Protein/genetics; Smad3 Protein/genetics; Syndecan-4/genetics; Transforming Growth Factor beta1/pharmacology; p38 Mitogen-Activated Protein Kinases/genetics; Animals; Aorta/cytology; Aorta/drug effects; Aorta/metabolism; Cattle; Endothelial Cells/cytology; Endothelial Cells/metabolism; Gene Expression Regulation; Primary Cell Culture; Protein Serine-Threonine Kinases/genetics; Protein Serine-Threonine Kinases/metabolism; RNA, Small Interfering/genetics; RNA, Small Interfering/metabolism; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta/genetics; Receptors, Transforming Growth Factor beta/metabolism; Signal Transduction; Smad2 Protein/antagonists & inhibitors; Smad2 Protein/metabolism; Smad3 Protein/antagonists & inhibitors; Smad3 Protein/metabolism; Syndecan-4/antagonists & inhibitors; Syndecan-4/metabolism; Time Factors; Transforming Growth Factor beta1/metabolism; p38 Mitogen-Activated Protein Kinases/antagonists & inhibitors; p38 Mitogen-Activated Protein Kinases/metabolism

Key words

ENDOTHELIAL CELL; PROTEOGLYCAN; SYNDECAN-4; TGF-ß

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Endothelial Cells / P38 Mitogen-Activated Protein Kinases / Smad2 Protein / Smad3 Protein / Transforming Growth Factor beta1 / Syndecan-4 Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Cell Biochem Year: 2017 Document type: Article Affiliation country: Japan

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