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Bifunctional conjugates with potent inhibitory activity towards cyclooxygenase and histone deacetylase.
Raji, Idris; Yadudu, Fatima; Janeira, Emily; Fathi, Shaghayegh; Szymczak, Lindsey; Kornacki, James Richard; Komatsu, Kensei; Li, Jian-Dong; Mrksich, Milan; Oyelere, Adegboyega K.
Affiliation
  • Raji I; School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332-0400, USA.
  • Yadudu F; School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332-0400, USA.
  • Janeira E; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA.
  • Fathi S; School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332-0400, USA.
  • Szymczak L; Departments of Chemistry and Biomedical Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208-3113, USA.
  • Kornacki JR; Departments of Chemistry and Biomedical Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208-3113, USA.
  • Komatsu K; Center for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, USA.
  • Li JD; Center for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, USA.
  • Mrksich M; Departments of Chemistry and Biomedical Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208-3113, USA.
  • Oyelere AK; School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332-0400, USA; Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA 30332-0400, USA. Electronic address: aoyelere@gatech.edu.
Bioorg Med Chem ; 25(3): 1202-1218, 2017 02 01.
Article in En | MEDLINE | ID: mdl-28057407
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Indomethacin / Cyclooxygenase Inhibitors / Prostaglandin-Endoperoxide Synthases / Histone Deacetylase Inhibitors / Celecoxib / Histone Deacetylases / Antineoplastic Agents Limits: Humans Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2017 Document type: Article Affiliation country: United States Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Indomethacin / Cyclooxygenase Inhibitors / Prostaglandin-Endoperoxide Synthases / Histone Deacetylase Inhibitors / Celecoxib / Histone Deacetylases / Antineoplastic Agents Limits: Humans Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2017 Document type: Article Affiliation country: United States Country of publication: United kingdom