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First-in-human trial of an anti-5T4 antibody-monomethylauristatin conjugate, PF-06263507, in patients with advanced solid tumors.
Shapiro, Geoffrey I; Vaishampayan, Ulka N; LoRusso, Patricia; Barton, Jeremy; Hua, Steven; Reich, Steven D; Shazer, Ronald; Taylor, Carrie T; Xuan, Dawei; Borghaei, Hossein.
Affiliation
  • Shapiro GI; Early Drug Development Center, Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Ave, Mayer 446, Boston, MA, 02215, USA. geoffrey_shapiro@dfci.harvard.edu.
  • Vaishampayan UN; Karmanos Cancer Institute, Detroit, MI, USA.
  • LoRusso P; Yale University, New Haven, CT, USA.
  • Barton J; Pfizer Oncology, La Jolla, CA, USA.
  • Hua S; Pfizer Oncology, La Jolla, CA, USA.
  • Reich SD; Pfizer Oncology, La Jolla, CA, USA.
  • Shazer R; Pfizer Oncology, La Jolla, CA, USA.
  • Taylor CT; Pfizer Oncology, La Jolla, CA, USA. Carrie.Taylor@pfizer.com.
  • Xuan D; Pfizer Early Oncology Development and Clinical Research, 10777 Science Center Drive, CB-1, San Diego, CA, 92121, USA. Carrie.Taylor@pfizer.com.
  • Borghaei H; Pfizer Oncology, La Jolla, CA, USA.
Invest New Drugs ; 35(3): 315-323, 2017 06.
Article in En | MEDLINE | ID: mdl-28070718
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligopeptides / Membrane Glycoproteins / Immunoconjugates / Antibodies, Monoclonal, Humanized / Antigens, Neoplasm / Neoplasms Type of study: Clinical_trials Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Invest New Drugs Year: 2017 Document type: Article Affiliation country: United States
Fulltext
Add to My VHL
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligopeptides / Membrane Glycoproteins / Immunoconjugates / Antibodies, Monoclonal, Humanized / Antigens, Neoplasm / Neoplasms Type of study: Clinical_trials Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Invest New Drugs Year: 2017 Document type: Article Affiliation country: United States