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Profiling single-guide RNA specificity reveals a mismatch sensitive core sequence.
Zheng, Ting; Hou, Yingzi; Zhang, Pingjing; Zhang, Zhenxi; Xu, Ying; Zhang, Letian; Niu, Leilei; Yang, Yi; Liang, Da; Yi, Fan; Peng, Wei; Feng, Wenjian; Yang, Ying; Chen, Jianxin; Zhu, York Yuanyuan; Zhang, Li-He; Du, Quan.
Affiliation
  • Zheng T; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
  • Hou Y; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
  • Zhang P; Biomics Biotechnologies co. Ltd, Nantong 226016, Jiangsu Province, China.
  • Zhang Z; Small RNA Technology and Application Institute, Nantong University, Nantong 226016, Jiangsu Province, China.
  • Xu Y; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
  • Zhang L; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
  • Niu L; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
  • Yang Y; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
  • Liang D; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
  • Yi F; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
  • Peng W; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
  • Feng W; Biomics Biotechnologies co. Ltd, Nantong 226016, Jiangsu Province, China.
  • Yang Y; Small RNA Technology and Application Institute, Nantong University, Nantong 226016, Jiangsu Province, China.
  • Chen J; Biomics Biotechnologies co. Ltd, Nantong 226016, Jiangsu Province, China.
  • Zhu YY; Small RNA Technology and Application Institute, Nantong University, Nantong 226016, Jiangsu Province, China.
  • Zhang LH; Department of Stomatology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
  • Du Q; Biomics Biotechnologies co. Ltd, Nantong 226016, Jiangsu Province, China.
Sci Rep ; 7: 40638, 2017 01 18.
Article in En | MEDLINE | ID: mdl-28098181
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Base Sequence / RNA, Guide, Kinetoplastida / Base Pairing / Gene Expression Profiling Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Sci Rep Year: 2017 Document type: Article Affiliation country: China Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Base Sequence / RNA, Guide, Kinetoplastida / Base Pairing / Gene Expression Profiling Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Sci Rep Year: 2017 Document type: Article Affiliation country: China Country of publication: United kingdom