Distinct physiological effects of ß<sub>1</sub>- and ß<sub>2</sub>-adrenoceptors in mouse ventricular myocytes: insights from a compartmentalized mathematical model.

Rozier, Kelvin; Bondarenko, Vladimir E

Distinct physiological effects of ß₁- and ß₂-adrenoceptors in mouse ventricular myocytes: insights from a compartmentalized mathematical model.

Rozier, Kelvin; Bondarenko, Vladimir E.

Affiliation

Rozier K; Department of Mathematics and Statistics, Georgia State University, Atlanta, Georgia; and.
Bondarenko VE; Department of Mathematics and Statistics, Georgia State University, Atlanta, Georgia; and vbondarenko@gsu.edu.

Am J Physiol Cell Physiol ; 312(5): C595-C623, 2017 May 01.

Article in En | MEDLINE | ID: mdl-28122730

Subject(s)

Action Potentials/physiology; Calcium Signaling/physiology; Models, Cardiovascular; Myocytes, Cardiac/metabolism; Receptors, Adrenergic, beta-1/metabolism; Receptors, Adrenergic, beta-2/metabolism; Animals; Cells, Cultured; Computer Simulation; Heart Ventricles/cytology; Heart Ventricles/metabolism; Ion Channel Gating/physiology; Mice; Myocytes, Cardiac/cytology

Key words

calcium dynamics; cardiac action potential; isoproterenol; signaling systems; sodium dynamics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Action Potentials / Receptors, Adrenergic, beta-2 / Receptors, Adrenergic, beta-1 / Calcium Signaling / Myocytes, Cardiac / Models, Cardiovascular Type of study: Prognostic_studies Limits: Animals Language: En Journal: Am J Physiol Cell Physiol Journal subject: FISIOLOGIA Year: 2017 Document type: Article Country of publication: United States

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