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Blocking two-component signalling enhances Candida albicans virulence and reveals adaptive mechanisms that counteract sustained SAPK activation.
Day, Alison M; Smith, Deborah A; Ikeh, Mélanie A C; Haider, Mohammed; Herrero-de-Dios, Carmen M; Brown, Alistair J P; Morgan, Brian A; Erwig, Lars P; MacCallum, Donna M; Quinn, Janet.
Affiliation
  • Day AM; Institute for Cell and Molecular Biosciences, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Smith DA; Institute for Cell and Molecular Biosciences, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Ikeh MA; Institute for Cell and Molecular Biosciences, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Haider M; Aberdeen Fungal Group, Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom.
  • Herrero-de-Dios CM; Aberdeen Fungal Group, Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom.
  • Brown AJ; Aberdeen Fungal Group, Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom.
  • Morgan BA; Institute for Cell and Molecular Biosciences, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Erwig LP; Aberdeen Fungal Group, Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom.
  • MacCallum DM; Aberdeen Fungal Group, Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom.
  • Quinn J; Institute for Cell and Molecular Biosciences, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.
PLoS Pathog ; 13(1): e1006131, 2017 01.
Article in En | MEDLINE | ID: mdl-28135328
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Candida albicans / Fungal Proteins / Gene Expression Regulation, Fungal / Mitogen-Activated Protein Kinases / MAP Kinase Signaling System Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: PLoS Pathog Year: 2017 Document type: Article Affiliation country: United kingdom Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Candida albicans / Fungal Proteins / Gene Expression Regulation, Fungal / Mitogen-Activated Protein Kinases / MAP Kinase Signaling System Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: PLoS Pathog Year: 2017 Document type: Article Affiliation country: United kingdom Country of publication: United States