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Metabolism and disposition of the anticancer quinolone derivative vosaroxin, a novel inhibitor of topoisomerase II.
Nijenhuis, C M; Lucas, L; Rosing, H; Huitema, A D R; Mergui-Roelvink, M; Jamieson, G C; Fox, J A; Mould, D R; Schellens, J H M; Beijnen, J H.
Affiliation
  • Nijenhuis CM; Department of Pharmacy & Pharmacology, Antoni van Leeuwenhoek/The Netherlands Cancer Institute and MC Slotervaart, Amsterdam, The Netherlands. cynthianijenhuis@gmail.com.
  • Lucas L; Department of Pharmacy & Pharmacology, Antoni van Leeuwenhoek/The Netherlands Cancer Institute and MC Slotervaart, Amsterdam, The Netherlands.
  • Rosing H; Department of Pharmacy & Pharmacology, Antoni van Leeuwenhoek/The Netherlands Cancer Institute and MC Slotervaart, Amsterdam, The Netherlands.
  • Huitema ADR; Department of Pharmacy & Pharmacology, Antoni van Leeuwenhoek/The Netherlands Cancer Institute and MC Slotervaart, Amsterdam, The Netherlands.
  • Mergui-Roelvink M; Division of Clinical Pharmacology, Department of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Jamieson GC; Sunesis Pharmaceuticals, Inc., South San Francisco, CA, USA.
  • Fox JA; Sunesis Pharmaceuticals, Inc., South San Francisco, CA, USA.
  • Mould DR; Projections Research, Inc., Phoenixville, PA, USA.
  • Schellens JHM; Division of Clinical Pharmacology, Department of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Beijnen JH; Division of Pharmacoepidemiology and Clinical Pharmacology, Faculty of Science, Department of Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.
Invest New Drugs ; 35(4): 478-490, 2017 08.
Article in En | MEDLINE | ID: mdl-28138829
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiazoles / Topoisomerase II Inhibitors / Naphthyridines / Neoplasms Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Invest New Drugs Year: 2017 Document type: Article Affiliation country: Netherlands Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiazoles / Topoisomerase II Inhibitors / Naphthyridines / Neoplasms Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Invest New Drugs Year: 2017 Document type: Article Affiliation country: Netherlands Country of publication: United States