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Unbiased Metabolite Profiling of Schizophrenia Fibroblasts under Stressful Perturbations Reveals Dysregulation of Plasmalogens and Phosphatidylcholines.
Huang, Joanne H; Park, Hyoungjun; Iaconelli, Jonathan; Berkovitch, Shaunna S; Watmuff, Bradley; McPhie, Donna; Öngür, Dost; Cohen, Bruce M; Clish, Clary B; Karmacharya, Rakesh.
Affiliation
  • Huang JH; Center for Experimental Drugs and Diagnostics, Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Harvard Medical School and Massachusetts General Hospital , Boston, Massachusetts 02114, United States.
  • Park H; Chemical Biology Program, Broad Institute of Harvard and MIT , Cambridge, Massachusetts 02142, United States.
  • Iaconelli J; Institute of Neuroinformatics, ETH Zurich and University of Zurich , CH-8057, Zurich, Switzerland.
  • Berkovitch SS; Center for Experimental Drugs and Diagnostics, Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Harvard Medical School and Massachusetts General Hospital , Boston, Massachusetts 02114, United States.
  • Watmuff B; Chemical Biology Program, Broad Institute of Harvard and MIT , Cambridge, Massachusetts 02142, United States.
  • McPhie D; Center for Experimental Drugs and Diagnostics, Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Harvard Medical School and Massachusetts General Hospital , Boston, Massachusetts 02114, United States.
  • Öngür D; Chemical Biology Program, Broad Institute of Harvard and MIT , Cambridge, Massachusetts 02142, United States.
  • Cohen BM; Center for Experimental Drugs and Diagnostics, Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Harvard Medical School and Massachusetts General Hospital , Boston, Massachusetts 02114, United States.
  • Clish CB; Chemical Biology Program, Broad Institute of Harvard and MIT , Cambridge, Massachusetts 02142, United States.
  • Karmacharya R; Schizophrenia and Bipolar Disorder Program, Harvard Medical School and McLean Hospital , Belmont, Massachusetts 02478, United States.
J Proteome Res ; 16(2): 481-493, 2017 02 03.
Article in En | MEDLINE | ID: mdl-28152600
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphatidylcholines / Schizophrenia / Stress, Physiological / Plasmalogens / Metabolome / Fibroblasts Type of study: Observational_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: J Proteome Res Journal subject: BIOQUIMICA Year: 2017 Document type: Article Affiliation country: United States Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphatidylcholines / Schizophrenia / Stress, Physiological / Plasmalogens / Metabolome / Fibroblasts Type of study: Observational_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: J Proteome Res Journal subject: BIOQUIMICA Year: 2017 Document type: Article Affiliation country: United States Country of publication: United States