Ameliorating effect of Celastrus paniculatus standardized extract and its fractions on 3-nitropropionic acid induced neuronal damage in rats: possible antioxidant mechanism.

Malik, Jai; Karan, Maninder; Dogra, Rachna

Malik, Jai; Karan, Maninder; Dogra, Rachna.

Affiliation

Malik J; a University Institute of Pharmaceutical Sciences - Centre of Advanced Study, Panjab University , Chandigarh , India.
Karan M; a University Institute of Pharmaceutical Sciences - Centre of Advanced Study, Panjab University , Chandigarh , India.
Dogra R; a University Institute of Pharmaceutical Sciences - Centre of Advanced Study, Panjab University , Chandigarh , India.

Pharm Biol ; 55(1): 980-990, 2017 Dec.

Article in En | MEDLINE | ID: mdl-28164735

Subject(s)

Antioxidants/pharmacology; Brain/drug effects; Celastrus/chemistry; Huntington Disease/prevention & control; Nerve Degeneration; Neurons/drug effects; Neuroprotective Agents/pharmacology; Nitro Compounds; Oxidative Stress/drug effects; Plant Extracts/pharmacology; Propionates; Animals; Antioxidants/isolation & purification; Behavior, Animal/drug effects; Biomarkers/metabolism; Brain/metabolism; Brain/pathology; Brain/physiopathology; Chromatography, Thin Layer; Cognition/drug effects; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol/chemistry; Gait/drug effects; Huntington Disease/metabolism; Huntington Disease/physiopathology; Huntington Disease/psychology; Male; Memory/drug effects; Motor Activity/drug effects; Muscle Strength/drug effects; Neurons/metabolism; Neurons/pathology; Neuroprotective Agents/isolation & purification; Phytotherapy; Plant Extracts/isolation & purification; Plants, Medicinal; Rats, Wistar; Seeds; Solvents/chemistry; Time Factors

Key words

3-Nitropropionic acid; Huntington's disease; Jyotishmati; Malkangni

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Propionates / Brain / Plant Extracts / Huntington Disease / Oxidative Stress / Neuroprotective Agents / Celastrus / Nerve Degeneration / Neurons / Nitro Compounds Type of study: Prognostic_studies Language: En Journal: Pharm Biol Year: 2017 Document type: Article Affiliation country: India Country of publication: United kingdom

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google