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Histone deacetylase inhibitor MS-275 augments expression of a subset of IFN-γ-regulated genes in Toxoplasma gondii-infected macrophages but does not improve parasite control.
Sumpf, Kristina; Nast, Roswitha; Downie, Bryan; Salinas, Gabriela; Lüder, Carsten G K.
Affiliation
  • Sumpf K; Institute for Medical Microbiology, University Medical Center, Georg-August-University, Kreuzbergring 57, 37075 Göttingen, Germany.
  • Nast R; Institute for Medical Microbiology, University Medical Center, Georg-August-University, Kreuzbergring 57, 37075 Göttingen, Germany.
  • Downie B; Transcriptome and Genome Analysis Laboratory, University Medical Center, Georg-August-University, Justus-von-Liebig-Weg 11, 37077 Göttingen, Germany.
  • Salinas G; Transcriptome and Genome Analysis Laboratory, University Medical Center, Georg-August-University, Justus-von-Liebig-Weg 11, 37077 Göttingen, Germany.
  • Lüder CGK; Institute for Medical Microbiology, University Medical Center, Georg-August-University, Kreuzbergring 57, 37075 Göttingen, Germany. Electronic address: clueder@gwdg.de.
Exp Parasitol ; 180: 45-54, 2017 Sep.
Article in En | MEDLINE | ID: mdl-28189488
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Toxoplasma / Benzamides / Gene Expression / Interferon-gamma / Histone Deacetylase Inhibitors / Macrophages Limits: Animals Language: En Journal: Exp Parasitol Year: 2017 Document type: Article Affiliation country: Germany Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Toxoplasma / Benzamides / Gene Expression / Interferon-gamma / Histone Deacetylase Inhibitors / Macrophages Limits: Animals Language: En Journal: Exp Parasitol Year: 2017 Document type: Article Affiliation country: Germany Country of publication: United States