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Activation of Insulin-PI3K/Akt-p70S6K Pathway in Hepatic Stellate Cells Contributes to Fibrosis in Nonalcoholic Steatohepatitis.
Cai, Cindy X; Buddha, Hema; Castelino-Prabhu, Shobha; Zhang, Zhiwei; Britton, Robert S; Bacon, Bruce R; Neuschwander-Tetri, Brent A.
Affiliation
  • Cai CX; Division of Gastroenterology and Hepatology, Department of Internal Medicine, VA Loma Linda Healthcare System, Loma Linda University, 11201 Benton Street, Loma Linda, CA, 92357, USA. cindy.cai3@va.gov.
  • Buddha H; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Saint Louis University Liver Center, Saint Louis University School of Medicine, 3635 Vista Avenue at Grand Blvd, St. Louis, MO, 63110, USA. cindy.cai3@va.gov.
  • Castelino-Prabhu S; Division of Gastroenterology and Hepatology, Department of Internal Medicine, VA Loma Linda Healthcare System, Loma Linda University, 11201 Benton Street, Loma Linda, CA, 92357, USA.
  • Zhang Z; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Saint Louis University Liver Center, Saint Louis University School of Medicine, 3635 Vista Avenue at Grand Blvd, St. Louis, MO, 63110, USA.
  • Britton RS; Department of Pathology, VA Loma Linda Healthcare System, Loma Linda University, 11201 Benton Street, Loma Linda, CA, 92357, USA.
  • Bacon BR; Division of Nephrology, Department of Medicine, VA Loma Linda Healthcare System, Loma Linda University, 11201 Benton Street, Loma Linda, CA, 92357, USA.
  • Neuschwander-Tetri BA; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Saint Louis University Liver Center, Saint Louis University School of Medicine, 3635 Vista Avenue at Grand Blvd, St. Louis, MO, 63110, USA.
Dig Dis Sci ; 62(4): 968-978, 2017 04.
Article in En | MEDLINE | ID: mdl-28194671
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphatidylinositol 3-Kinases / Ribosomal Protein S6 Kinases, 70-kDa / Proto-Oncogene Proteins c-akt / Hepatic Stellate Cells / Non-alcoholic Fatty Liver Disease / Liver Cirrhosis Limits: Animals Language: En Journal: Dig Dis Sci Year: 2017 Document type: Article Affiliation country: United States Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphatidylinositol 3-Kinases / Ribosomal Protein S6 Kinases, 70-kDa / Proto-Oncogene Proteins c-akt / Hepatic Stellate Cells / Non-alcoholic Fatty Liver Disease / Liver Cirrhosis Limits: Animals Language: En Journal: Dig Dis Sci Year: 2017 Document type: Article Affiliation country: United States Country of publication: United States