Model for the formation of double minutes from prematurely condensed chromosomes of replicating micronuclei in drug-treated Chinese hamster ovary cells undergoing DNA amplification.

Sen, S; Hittelman, W N; Teeter, L D; Kuo, M T

Sen, S; Hittelman, W N; Teeter, L D; Kuo, M T.

Affiliation

Sen S; Division of Laboratory Medicine, University of Texas M.D. Anderson Cancer Center, Houston 77030.

Cancer Res ; 49(23): 6731-7, 1989 Dec 01.

Article in En | MEDLINE | ID: mdl-2819718

Subject(s)

Chromosome Aberrations; Chromosomes/ultrastructure; Gene Amplification; Animals; Cell Line; Cricetinae; Doxorubicin/pharmacology; Drug Resistance; Micronucleus Tests; Mitosis/drug effects; Vinblastine/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Gene Amplification / Chromosome Aberrations / Chromosomes Limits: Animals Language: En Journal: Cancer Res Year: 1989 Document type: Article Country of publication: United States

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