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Inhibition of PDE5A1 guanosine cyclic monophosphate (cGMP) hydrolysing activity by sildenafil analogues that inhibit cellular cGMP efflux.
Subbotina, Anna; Ravna, Aina W; Lysaa, Roy A; Abagyan, Ruben; Bugno, Ryszard; Sager, Georg.
Affiliation
  • Subbotina A; Experimental and Clinical Pharmacology, Department of Medical Biology, Faculty of Health Sciences, University of Tromsø - The Arctic University of Norway, Tromsø, Norway.
  • Ravna AW; Experimental and Clinical Pharmacology, Department of Medical Biology, Faculty of Health Sciences, University of Tromsø - The Arctic University of Norway, Tromsø, Norway.
  • Lysaa RA; Experimental and Clinical Pharmacology, Department of Medical Biology, Faculty of Health Sciences, University of Tromsø - The Arctic University of Norway, Tromsø, Norway.
  • Abagyan R; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California - San Diego, La Jolla, CA, USA.
  • Bugno R; Department of Medicinal Chemistry, Institute of Pharmacology, Polish Academy of Sciences, Kraków, Poland.
  • Sager G; Experimental and Clinical Pharmacology, Department of Medical Biology, Faculty of Health Sciences, University of Tromsø - The Arctic University of Norway, Tromsø, Norway.
J Pharm Pharmacol ; 69(6): 675-683, 2017 Jun.
Article in En | MEDLINE | ID: mdl-28211580
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphodiesterase Inhibitors / Cyclic GMP / Cyclic Nucleotide Phosphodiesterases, Type 5 / Sildenafil Citrate Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Pharm Pharmacol Year: 2017 Document type: Article Affiliation country: Norway Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphodiesterase Inhibitors / Cyclic GMP / Cyclic Nucleotide Phosphodiesterases, Type 5 / Sildenafil Citrate Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Pharm Pharmacol Year: 2017 Document type: Article Affiliation country: Norway Country of publication: United kingdom