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An engineered transforming growth factor ß (TGF-ß) monomer that functions as a dominant negative to block TGF-ß signaling.
Kim, Sun Kyung; Barron, Lindsey; Hinck, Cynthia S; Petrunak, Elyse M; Cano, Kristin E; Thangirala, Avinash; Iskra, Brian; Brothers, Molly; Vonberg, Machell; Leal, Belinda; Richter, Blair; Kodali, Ravindra; Taylor, Alexander B; Du, Shoucheng; Barnes, Christopher O; Sulea, Traian; Calero, Guillermo; Hart, P John; Hart, Matthew J; Demeler, Borries; Hinck, Andrew P.
Affiliation
  • Kim SK; the Departments of Biochemistry and Structural Biology and.
  • Barron L; Cell Systems and Anatomy.
  • Hinck CS; From the Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15260.
  • Petrunak EM; From the Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15260.
  • Cano KE; the Departments of Biochemistry and Structural Biology and.
  • Thangirala A; the Departments of Biochemistry and Structural Biology and.
  • Iskra B; the Departments of Biochemistry and Structural Biology and.
  • Brothers M; the Departments of Biochemistry and Structural Biology and.
  • Vonberg M; the Departments of Biochemistry and Structural Biology and.
  • Leal B; the Departments of Biochemistry and Structural Biology and.
  • Richter B; the Departments of Biochemistry and Structural Biology and.
  • Kodali R; From the Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15260.
  • Taylor AB; the Departments of Biochemistry and Structural Biology and.
  • Du S; From the Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15260.
  • Barnes CO; From the Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15260.
  • Sulea T; the National Research Council, Human Health Therapeutics Portfolio, Montréal, Quebec H4P 2R2, Canada.
  • Calero G; From the Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15260.
  • Hart PJ; the Departments of Biochemistry and Structural Biology and.
  • Hart MJ; Center for Innovative Drug Discovery, University of Texas Health Science Center, San Antonio, Texas 78229-3900, and.
  • Demeler B; the Departments of Biochemistry and Structural Biology and.
  • Hinck AP; From the Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15260, ahinck@pitt.edu.
J Biol Chem ; 292(17): 7173-7188, 2017 04 28.
Article in En | MEDLINE | ID: mdl-28228478
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Engineering / Signal Transduction / Transforming Growth Factor beta / Protein Serine-Threonine Kinases / Receptors, Transforming Growth Factor beta Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2017 Document type: Article Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Engineering / Signal Transduction / Transforming Growth Factor beta / Protein Serine-Threonine Kinases / Receptors, Transforming Growth Factor beta Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2017 Document type: Article Country of publication: United States