Cytotoxic and toxicogenomic effects of silibinin in bladder cancer cells with different TP53 status.

DE Oliveira, Daiane Teixeira; Savio, Andre Luiz Ventura; Marcondes, Joao Paulo DE Castro; Barros, Tatiane Martins; Barbosa, Ludmila Correia; Salvadori, Daisy Maria Favero; DA Silva, Glenda Nicioli

DE Oliveira, Daiane Teixeira; Savio, Andre Luiz Ventura; Marcondes, Joao Paulo DE Castro; Barros, Tatiane Martins; Barbosa, Ludmila Correia; Salvadori, Daisy Maria Favero; DA Silva, Glenda Nicioli.

Affiliation

DE Oliveira DT; Escola de Farmacia, Departamento de Analises Clinicas, Universidade Federal de Ouro Preto, Ouro Preto, MG, Brazil.

J Biosci ; 42(1): 91-101, 2017 Mar.

Article in En | MEDLINE | ID: mdl-28229968

Subject(s)

Cell Proliferation/drug effects; Silymarin/administration & dosage; Tumor Suppressor Protein p53/genetics; Urinary Bladder Neoplasms/drug therapy; Apoptosis/drug effects; Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases/biosynthesis; DNA Damage/drug effects; Gene Expression Regulation, Neoplastic/drug effects; Humans; MicroRNAs/biosynthesis; Proto-Oncogene Proteins c-akt/biosynthesis; Receptor, Fibroblast Growth Factor, Type 3/biosynthesis; Silybin; Silymarin/adverse effects; TOR Serine-Threonine Kinases/biosynthesis; Urinary Bladder Neoplasms/genetics; Urinary Bladder Neoplasms/pathology

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Collection: 01-internacional Database: MEDLINE Main subject: Silymarin / Urinary Bladder Neoplasms / Tumor Suppressor Protein p53 / Cell Proliferation Limits: Humans Language: En Journal: J Biosci Year: 2017 Document type: Article Affiliation country: Brazil

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