Adiponectin partially rescues high glucose/high fat-induced impairment of mitochondrial biogenesis and function in a PGC-1&#945; dependent manner.

Wang, H; Yan, W-J; Zhang, J-L; Zhang, F-Y; Gao, C; Wang, Y-J; Bond Law, W; Tao, L

Adiponectin partially rescues high glucose/high fat-induced impairment of mitochondrial biogenesis and function in a PGC-1α dependent manner.

Wang, H; Yan, W-J; Zhang, J-L; Zhang, F-Y; Gao, C; Wang, Y-J; Bond Law, W; Tao, L.

Affiliation

Wang H; Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xian, China. lingtao@fmmu.edu.cn.

Eur Rev Med Pharmacol Sci ; 21(3): 590-599, 2017 01.

Article in En | MEDLINE | ID: mdl-28239807

Subject(s)

Adiponectin/pharmacology; Myocytes, Cardiac/cytology; Organelle Biogenesis; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/metabolism; Animals; Apoptosis; Cells, Cultured; Culture Media/chemistry; Diabetes Mellitus, Type 2/physiopathology; Glucose/pharmacology; Mitochondria/drug effects; Mitochondria/pathology; Myocytes, Cardiac/metabolism; Rats

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Collection: 01-internacional Database: MEDLINE Main subject: Organelle Biogenesis / Myocytes, Cardiac / Adiponectin / Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha Limits: Animals Language: En Journal: Eur Rev Med Pharmacol Sci Journal subject: FARMACOLOGIA / TOXICOLOGIA Year: 2017 Document type: Article Affiliation country: China

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