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Galectin-3 is a non-classic RNA binding protein that stabilizes the mucin MUC4 mRNA in the cytoplasm of cancer cells.
Coppin, Lucie; Vincent, Audrey; Frénois, Frédéric; Duchêne, Belinda; Lahdaoui, Fatima; Stechly, Laurence; Renaud, Florence; Villenet, Céline; Van Seuningen, Isabelle; Leteurtre, Emmanuelle; Dion, Johann; Grandjean, Cyrille; Poirier, Françoise; Figeac, Martin; Delacour, Delphine; Porchet, Nicole; Pigny, Pascal.
Affiliation
  • Coppin L; Univ. Lille, UMR-S 1172 - JPARC - Jean-Pierre Aubert Research Center, F-59000 Lille, France.
  • Vincent A; Inserm, UMR-S 1172, Team "Mucins, Epithelial Differentiation and Carcinogenesis", F-59000 Lille, France.
  • Frénois F; CHU Lille, Service de Biochimie « Hormonologie, Métabolisme-Nutrition, Oncologie ¼, F-59000 Lille, France.
  • Duchêne B; Univ. Lille, UMR-S 1172 - JPARC - Jean-Pierre Aubert Research Center, F-59000 Lille, France.
  • Lahdaoui F; Inserm, UMR-S 1172, Team "Mucins, Epithelial Differentiation and Carcinogenesis", F-59000 Lille, France.
  • Stechly L; Univ. Lille, RADEME (Research team on rare developmental and metabolic diseases), F-59000 Lille, France.
  • Renaud F; Univ. Lille, UMR-S 1172 - JPARC - Jean-Pierre Aubert Research Center, F-59000 Lille, France.
  • Villenet C; Inserm, UMR-S 1172, Team "Mucins, Epithelial Differentiation and Carcinogenesis", F-59000 Lille, France.
  • Van Seuningen I; Univ. Lille, UMR-S 1172 - JPARC - Jean-Pierre Aubert Research Center, F-59000 Lille, France.
  • Leteurtre E; Inserm, UMR-S 1172, Team "Mucins, Epithelial Differentiation and Carcinogenesis", F-59000 Lille, France.
  • Dion J; CHU Lille, Service de Biochimie « Hormonologie, Métabolisme-Nutrition, Oncologie ¼, F-59000 Lille, France.
  • Grandjean C; Univ. Lille, UMR-S 1172 - JPARC - Jean-Pierre Aubert Research Center, F-59000 Lille, France.
  • Poirier F; Inserm, UMR-S 1172, Team "Mucins, Epithelial Differentiation and Carcinogenesis", F-59000 Lille, France.
  • Figeac M; CHU Lille, Service d'anatomie-cytologie-pathologie, F-59000 Lille, France.
  • Delacour D; Univ. Lille, CHU Lille, Plate-forme de génomique fonctionnelle, Centre de Biologie et Pathologie, F-59037 Lille cedex, France.
  • Porchet N; Univ. Lille, UMR-S 1172 - JPARC - Jean-Pierre Aubert Research Center, F-59000 Lille, France.
  • Pigny P; Inserm, UMR-S 1172, Team "Mucins, Epithelial Differentiation and Carcinogenesis", F-59000 Lille, France.
Sci Rep ; 7: 43927, 2017 03 06.
Article in En | MEDLINE | ID: mdl-28262838

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / RNA, Messenger / Cytoplasm / Galectin 3 / Epithelial Cells / Mucin-4 Limits: Animals / Humans Language: En Journal: Sci Rep Year: 2017 Document type: Article Affiliation country: France Country of publication: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / RNA, Messenger / Cytoplasm / Galectin 3 / Epithelial Cells / Mucin-4 Limits: Animals / Humans Language: En Journal: Sci Rep Year: 2017 Document type: Article Affiliation country: France Country of publication: United kingdom