Reactive Retinal Astrocytic Tumor (Focal Nodular Gliosis): A Case Report.
Ocul Oncol Pathol
; 3(1): 1-7, 2017 Jan.
Article
in En
| MEDLINE
| ID: mdl-28275595
ABSTRACT
PURPOSE:
To report the clinical and histopathological findings of a reactive retinal astrocytic tumor (RRAT) that progressed to massive retinal gliosis. OBSERVATIONS The patient presented with an elevated, white-yellow retinal mass and extensive retinal exudation in the left eye. Progressive enlargement of the mass and proliferative vitreoretinopathy eventually led to phthisis bulbi and enucleation. Histologically, the mass showed a predominant astrocytic component with intense glial fibrillary acidic protein staining, hyperplasia, fibrous metaplasia, and osseous metaplasia of the retinal pigment epithelium. The Ki-67 proliferative index was <5%, and few scattered vascular channels were observed. CONCLUSIONS AND IMPORTANCE These findings show that this tumor is the result of a reactive glial process rather than of neoplastic vascular proliferation. Massive retinal gliosis probably represents the advanced stage of RRAT.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Ocul Oncol Pathol
Year:
2017
Document type:
Article
Affiliation country:
United States