Moderate, Short-Term, Local Hyperglycemia Attenuates Forearm Endothelium-Dependent Vasodilation After Transient Ischemia-Reperfusion in Human Volunteers.

Ebert, Thomas J; Novalija, Jutta; Barney, Jill A; Uhrich, Toni D; Arain, Shahbaz R; Freed, Julie K; Pagel, Paul S

Ebert, Thomas J; Novalija, Jutta; Barney, Jill A; Uhrich, Toni D; Arain, Shahbaz R; Freed, Julie K; Pagel, Paul S.

Affiliation

Ebert TJ; Anesthesia Service, the Clement J. Zablocki Veterans Affairs Medical Center, Milwaukee, WI. Electronic address: tjebert@mcw.edu.
Novalija J; Anesthesia Service, the Clement J. Zablocki Veterans Affairs Medical Center, Milwaukee, WI.
Barney JA; Anesthesia Service, the Clement J. Zablocki Veterans Affairs Medical Center, Milwaukee, WI.
Uhrich TD; Anesthesia Service, the Clement J. Zablocki Veterans Affairs Medical Center, Milwaukee, WI.
Arain SR; Anesthesia Service, the Clement J. Zablocki Veterans Affairs Medical Center, Milwaukee, WI.
Freed JK; Anesthesia Service, the Clement J. Zablocki Veterans Affairs Medical Center, Milwaukee, WI.
Pagel PS; Anesthesia Service, the Clement J. Zablocki Veterans Affairs Medical Center, Milwaukee, WI.

J Cardiothorac Vasc Anesth ; 31(5): 1649-1655, 2017 Oct.

Article in En | MEDLINE | ID: mdl-28284926

Subject(s)

Endothelium, Vascular/physiology; Forearm/physiology; Hyperglycemia/physiopathology; Regional Blood Flow/physiology; Reperfusion Injury/physiopathology; Vasodilation/physiology; Acute Disease; Adult; Cross-Over Studies; Double-Blind Method; Endothelium, Vascular/drug effects; Female; Forearm/blood supply; Glucose/administration & dosage; Glucose/adverse effects; Healthy Volunteers; Humans; Hyperglycemia/chemically induced; Hyperglycemia/diagnosis; Infusions, Intra-Arterial; Male; Pilot Projects; Regional Blood Flow/drug effects; Reperfusion Injury/complications; Reperfusion Injury/diagnosis; Single-Blind Method; Vasodilation/drug effects; Young Adult

Key words

acetylcholine; endothelium; forearm blood flow; hyperglycemia; ischemia-reperfusion injury; vascular reactivity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Regional Blood Flow / Vasodilation / Endothelium, Vascular / Reperfusion Injury / Forearm / Hyperglycemia Type of study: Clinical_trials / Diagnostic_studies / Prognostic_studies Limits: Adult / Female / Humans / Male Language: En Journal: J Cardiothorac Vasc Anesth Journal subject: ANESTESIOLOGIA / CARDIOLOGIA Year: 2017 Document type: Article Country of publication: United States

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