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DNA damage during S-phase mediates the proliferation-quiescence decision in the subsequent G1 via p21 expression.
Barr, Alexis R; Cooper, Samuel; Heldt, Frank S; Butera, Francesca; Stoy, Henriette; Mansfeld, Jörg; Novák, Béla; Bakal, Chris.
Affiliation
  • Barr AR; Division of Cancer Biology, The Institute of Cancer Research, 237 Fulham Road, London SW3 6JB, UK.
  • Cooper S; Division of Cancer Biology, The Institute of Cancer Research, 237 Fulham Road, London SW3 6JB, UK.
  • Heldt FS; Department of Computational Systems Medicine, Imperial College, South Kensington Campus, London SW7 2AZ, UK.
  • Butera F; Department of Biochemistry, OCISB, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.
  • Stoy H; Division of Cancer Biology, The Institute of Cancer Research, 237 Fulham Road, London SW3 6JB, UK.
  • Mansfeld J; Division of Cancer Biology, The Institute of Cancer Research, 237 Fulham Road, London SW3 6JB, UK.
  • Novák B; Cell Cycle, Biotechnology Centre, TU Dresden, 01307 Dresden, Germany.
  • Bakal C; Department of Biochemistry, OCISB, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.
Nat Commun ; 8: 14728, 2017 03 20.
Article in En | MEDLINE | ID: mdl-28317845
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Damage / G1 Phase / S Phase / Cell Proliferation / Cyclin-Dependent Kinase Inhibitor p21 Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2017 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Damage / G1 Phase / S Phase / Cell Proliferation / Cyclin-Dependent Kinase Inhibitor p21 Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2017 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom