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MultiTEP platform-based DNA epitope vaccine targeting N-terminus of tau induces strong immune responses and reduces tau pathology in THY-Tau22 mice.
Davtyan, Hayk; Chen, Wesley W; Zagorski, Karen; Davis, Joy; Petrushina, Irina; Kazarian, Konstantin; Cribbs, David H; Agadjanyan, Michael G; Blurton-Jones, Mathew; Ghochikyan, Anahit.
Affiliation
  • Davtyan H; The Institute for Molecular Medicine, Huntington Beach, CA 92647, United States.
  • Chen WW; Department of Neurobiology & Behavior, University of California Irvine, Irvine, CA 92697, United States.
  • Zagorski K; The Institute for Molecular Medicine, Huntington Beach, CA 92647, United States.
  • Davis J; Sue and Bill Gross Stem Cell Research Center, University of California Irvine, Irvine, CA 92697, United States; Institute for Memory Impairments and Neurological Disorders, University of California Irvine, Irvine, CA 92697, United States.
  • Petrushina I; Institute for Memory Impairments and Neurological Disorders, University of California Irvine, Irvine, CA 92697, United States.
  • Kazarian K; The Institute for Molecular Medicine, Huntington Beach, CA 92647, United States.
  • Cribbs DH; Institute for Memory Impairments and Neurological Disorders, University of California Irvine, Irvine, CA 92697, United States.
  • Agadjanyan MG; The Institute for Molecular Medicine, Huntington Beach, CA 92647, United States; Institute for Memory Impairments and Neurological Disorders, University of California Irvine, Irvine, CA 92697, United States.
  • Blurton-Jones M; Department of Neurobiology & Behavior, University of California Irvine, Irvine, CA 92697, United States; Sue and Bill Gross Stem Cell Research Center, University of California Irvine, Irvine, CA 92697, United States; Institute for Memory Impairments and Neurological Disorders, University of Cali
  • Ghochikyan A; The Institute for Molecular Medicine, Huntington Beach, CA 92647, United States. Electronic address: aghochikyan@immed.org.
Vaccine ; 35(16): 2015-2024, 2017 04 11.
Article in En | MEDLINE | ID: mdl-28320590
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tau Proteins / Vaccines, DNA / Alzheimer Disease / Epitopes Limits: Animals / Female / Humans Language: En Journal: Vaccine Year: 2017 Document type: Article Affiliation country: United States
Fulltext
Add to My VHL
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tau Proteins / Vaccines, DNA / Alzheimer Disease / Epitopes Limits: Animals / Female / Humans Language: En Journal: Vaccine Year: 2017 Document type: Article Affiliation country: United States