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Discovery of novel curcumin derivatives targeting xanthine oxidase and urate transporter 1 as anti-hyperuricemic agents.
Ao, Gui-Zhen; Zhou, Meng-Ze; Li, Yu-Yao; Li, Si-Ning; Wang, Hua-Nian; Wan, Qian-Wen; Li, Huan-Qiu; Hu, Qing-Hua.
Affiliation
  • Ao GZ; Department of Medicinal Chemistry, College of Pharmaceutical Sciences, Soochow University, Suzhou 215123, PR China.
  • Zhou MZ; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, PR China.
  • Li YY; Department of Medicinal Chemistry, College of Pharmaceutical Sciences, Soochow University, Suzhou 215123, PR China.
  • Li SN; Department of Medicinal Chemistry, College of Pharmaceutical Sciences, Soochow University, Suzhou 215123, PR China.
  • Wang HN; Department of Medicinal Chemistry, College of Pharmaceutical Sciences, Soochow University, Suzhou 215123, PR China.
  • Wan QW; Department of Medicinal Chemistry, College of Pharmaceutical Sciences, Soochow University, Suzhou 215123, PR China.
  • Li HQ; Department of Medicinal Chemistry, College of Pharmaceutical Sciences, Soochow University, Suzhou 215123, PR China. Electronic address: huanqiuli@suda.edu.cn.
  • Hu QH; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, PR China. Electronic address: huqh@cpu.edu.cn.
Bioorg Med Chem ; 25(1): 166-174, 2017 01 01.
Article in En | MEDLINE | ID: mdl-28340987
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Xanthine Oxidase / Curcumin / Organic Anion Transporters / Organic Cation Transport Proteins / Hyperuricemia / Enzyme Inhibitors Limits: Animals / Humans / Male Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2017 Document type: Article Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Xanthine Oxidase / Curcumin / Organic Anion Transporters / Organic Cation Transport Proteins / Hyperuricemia / Enzyme Inhibitors Limits: Animals / Humans / Male Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2017 Document type: Article Country of publication: United kingdom