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Induction of apoptotic DNA fragmentation mediated by mitochondrial pathway with caspase-3-dependent BID cleavage in human gastric cancer cells by a new nitroxyl spin-labeled derivative of podophyllotoxin.
Yang, Yu-Jie; Qi, She-Ning; Shi, Rui-Yue; Yao, Jun; Wang, Li-Sheng; Yuan, Hu-Qin; Jing, Yuan-Xue.
Affiliation
  • Yang YJ; Department of Gastroenterology, The Second Clinical Medical College, Jinan University, Shenzhen 518020, China.
  • Qi SN; Department of Histology and Embryology, School of Basic Medicine, Lanzhou University, Key Laboratory of Pre-clinical Study for New Drugs of Gansu Province, Lanzhou 730000, China. Electronic address: qishn@lzu.edu.cn.
  • Shi RY; Department of Gastroenterology, The Second Clinical Medical College, Jinan University, Shenzhen 518020, China.
  • Yao J; Department of Gastroenterology, The Second Clinical Medical College, Jinan University, Shenzhen 518020, China.
  • Wang LS; Department of Gastroenterology, The Second Clinical Medical College, Jinan University, Shenzhen 518020, China. Electronic address: wangls168@163.com.
  • Yuan HQ; Department of Gastrointestinal Oncology Surgery, Tumor Hospital of Gansu Province, Lanzhou 730050, China.
  • Jing YX; Reproductive Hospital, The First Clinical Medical College, Lanzhou University, Lanzhou 730000, China.
Biomed Pharmacother ; 90: 131-138, 2017 Jun.
Article in En | MEDLINE | ID: mdl-28347917
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Podophyllotoxin / Stomach Neoplasms / Apoptosis / Caspase 3 / DNA Fragmentation / Mitochondria / Antineoplastic Agents, Phytogenic Limits: Humans Language: En Journal: Biomed Pharmacother Year: 2017 Document type: Article Affiliation country: China Country of publication: France
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Podophyllotoxin / Stomach Neoplasms / Apoptosis / Caspase 3 / DNA Fragmentation / Mitochondria / Antineoplastic Agents, Phytogenic Limits: Humans Language: En Journal: Biomed Pharmacother Year: 2017 Document type: Article Affiliation country: China Country of publication: France