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Mutational spectra of aflatoxin B1 in vivo establish biomarkers of exposure for human hepatocellular carcinoma.
Chawanthayatham, Supawadee; Valentine, Charles C; Fedeles, Bogdan I; Fox, Edward J; Loeb, Lawrence A; Levine, Stuart S; Slocum, Stephen L; Wogan, Gerald N; Croy, Robert G; Essigmann, John M.
Affiliation
  • Chawanthayatham S; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Valentine CC; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Fedeles BI; Center for Environmental Health Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Fox EJ; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Loeb LA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Levine SS; Center for Environmental Health Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Slocum SL; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Wogan GN; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Croy RG; Center for Environmental Health Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Essigmann JM; Department of Pathology, University of Washington, Seattle, WA 98195.
Proc Natl Acad Sci U S A ; 114(15): E3101-E3109, 2017 04 11.
Article in En | MEDLINE | ID: mdl-28351974
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biomarkers / Aflatoxin B1 / Carcinoma, Hepatocellular / DNA Adducts / Carcinogenesis / Liver Neoplasms / Mutation Type of study: Prognostic_studies / Risk_factors_studies / Screening_studies Limits: Animals / Female / Humans / Male Language: En Journal: Proc Natl Acad Sci U S A Year: 2017 Document type: Article Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biomarkers / Aflatoxin B1 / Carcinoma, Hepatocellular / DNA Adducts / Carcinogenesis / Liver Neoplasms / Mutation Type of study: Prognostic_studies / Risk_factors_studies / Screening_studies Limits: Animals / Female / Humans / Male Language: En Journal: Proc Natl Acad Sci U S A Year: 2017 Document type: Article Country of publication: United States