Red blood cells galactose-1-P-urydil transferase in senile and presenile cataracts.
Metab Pediatr Syst Ophthalmol (1985)
; 8(4): 160-1, 1985.
Article
in En
| MEDLINE
| ID: mdl-2836694
ABSTRACT
There are conflicting reports in the literature regarding the role of partial deficiency of "galactosemic" enzymes (galactose-1-P-urydil transferase and galactokinase) in the development of infantile and presenile cataract. The AA. have investigated the levels of Red Blood Cell Galactose-1-P-urydil transferase in 39 cataractous patients and in 22 age matched controls. A weak correlation between the enzymatic activity deficiency and the presenile cataract has been identified. The results suggest that a chronic impairment of galactose metabolism may be a contributory risk factor in the pathogenesis of presenile cataracts; however, further investigations are required to assess the actual significance of the findings of the present paper.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cataract
/
UTP-Hexose-1-Phosphate Uridylyltransferase
/
Erythrocytes
/
Nucleotidyltransferases
Type of study:
Prognostic_studies
/
Risk_factors_studies
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Metab Pediatr Syst Ophthalmol (1985)
Year:
1985
Document type:
Article
Affiliation country:
Italy