Cysts; Glucosyltransferases; Heterozygote; Liver Diseases; Mutation; SEC Translocation Channels; TRPP Cation Channels; Adult; Animals; Calcium-Binding Proteins; Cell Line, Transformed; Cysts/genetics; Cysts/metabolism; Endoplasmic Reticulum/genetics; Endoplasmic Reticulum/metabolism; Female; Genome-Wide Association Study; Glucosidases/genetics; Glucosidases/metabolism; Glucosyltransferases/genetics; Glucosyltransferases/metabolism; Humans; Intracellular Signaling Peptides and Proteins/genetics; Intracellular Signaling Peptides and Proteins/metabolism; Liver Diseases/genetics; Liver Diseases/metabolism; Male; Membrane Proteins/genetics; Membrane Proteins/metabolism; Mice; Molecular Chaperones; RNA-Binding Proteins; SEC Translocation Channels/genetics; SEC Translocation Channels/metabolism; TRPP Cation Channels/biosynthesis; TRPP Cation Channels/genetics