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Rational Re-Engineering of the O-Dealkylation of 7-Alkoxycoumarin Derivatives by Cytochromes P450 2B from the Desert Woodrat Neotoma lepida.
Huo, Lu; Liu, Jingbao; Dearing, M Denise; Szklarz, Grazyna D; Halpert, James R; Wilderman, P Ross.
Affiliation
  • Huo L; Department of Pharmaceutical Science, University of Connecticut School of Pharmacy , Storrs, Connecticut 06269-3092, United States.
  • Liu J; Department of Pharmaceutical Science, University of Connecticut School of Pharmacy , Storrs, Connecticut 06269-3092, United States.
  • Dearing MD; Department of Biology, University of Utah , Salt Lake City, Utah 84112, United States.
  • Szklarz GD; Department of Pharmaceutical Sciences, West Virginia University School of Pharmacy , Morgantown, West Virginia 26506, United States.
  • Halpert JR; Department of Pharmaceutical Science, University of Connecticut School of Pharmacy , Storrs, Connecticut 06269-3092, United States.
  • Wilderman PR; Department of Pharmaceutical Science, University of Connecticut School of Pharmacy , Storrs, Connecticut 06269-3092, United States.
Biochemistry ; 56(16): 2238-2246, 2017 04 25.
Article in En | MEDLINE | ID: mdl-28375626
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Coumarins / Cytochrome P-450 Enzyme System Limits: Animals Language: En Journal: Biochemistry Year: 2017 Document type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Coumarins / Cytochrome P-450 Enzyme System Limits: Animals Language: En Journal: Biochemistry Year: 2017 Document type: Article Affiliation country: United States