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Specific Polysaccharide Antibody Deficiency Revealed by Severe Bacterial Infections in Adulthood: A Report on 11 Cases.
Lopez, Benjamin; Boucher, Anne; Bahuaud, Mathilde; Mortuaire, Geoffrey; Melliez, Hugues; Launay, David; Terriou, Louis; Wemeau-Stervinou, Lidwine; Wallaert, Benoît; Faure, Karine; Wallet, Frédéric; Hachulla, Eric; Hatron, Pierre-Yves; Dubucquoi, Sylvain; Batteux, Frédéric; Labalette, Myriam; Lefèvre, Guillaume.
Affiliation
  • Lopez B; CHU Lille, Institut d'Immunologie.
  • Boucher A; University of Lille, Inflammation Research International Center.
  • Bahuaud M; CHU Lille, Département de Médecine Interne et Immunologie Clinique, Centre National de Référence Maladies Systémiques et Auto-immunes Rares.
  • Mortuaire G; CHU Hôpital Cochin, Laboratoire d'Immunologie biologique, Plateforme d'Immuno-monitoring Vaccinal, Paris.
  • Melliez H; CHU Lille, Service Oto-Rhino-Laryngologie et Chirurgie cervico-faciale.
  • Launay D; Service Universitaire Régional de Maladies Infectieuses et du Voyageur, Centre Hospitalier Gustave Dron, Tourcoing.
  • Terriou L; University of Lille, Inflammation Research International Center.
  • Wemeau-Stervinou L; CHU Lille, Département de Médecine Interne et Immunologie Clinique, Centre National de Référence Maladies Systémiques et Auto-immunes Rares.
  • Wallaert B; University of Lille, Inflammation Research International Center.
  • Faure K; CHU Lille, Service de Pneumologie et Immuno-Allergologie, Centre de compétence Maladies Pulmonaires Rares.
  • Wallet F; CHU Lille, Service de Pneumologie et Immuno-Allergologie, Centre de compétence Maladies Pulmonaires Rares.
  • Hachulla E; CHU Lille, Unité des Maladies Infectieuses.
  • Hatron PY; CHU Lille, Institut de Microbiologie, France.
  • Dubucquoi S; University of Lille, Inflammation Research International Center.
  • Batteux F; CHU Lille, Département de Médecine Interne et Immunologie Clinique, Centre National de Référence Maladies Systémiques et Auto-immunes Rares.
  • Labalette M; CHU Lille, Département de Médecine Interne et Immunologie Clinique, Centre National de Référence Maladies Systémiques et Auto-immunes Rares.
  • Lefèvre G; CHU Lille, Institut d'Immunologie.
Clin Infect Dis ; 65(2): 328-331, 2017 Jul 15.
Article in En | MEDLINE | ID: mdl-28379361
ABSTRACT
We report on 11 cases of specific polysaccharide antibody deficiency (SPAD) revealed in adulthood by severe infections with encapsulated bacteria. Given that immunoglobulin replacement therapy can effectively prevent the recurrence of bacterial infections in this context, SPAD should be considered once other antibody deficiencies have been ruled out.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polysaccharides, Bacterial / Bacterial Infections / Immunologic Deficiency Syndromes / Antibodies, Bacterial Limits: Adolescent / Adult / Female / Humans / Male / Middle aged Language: En Journal: Clin Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2017 Document type: Article
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polysaccharides, Bacterial / Bacterial Infections / Immunologic Deficiency Syndromes / Antibodies, Bacterial Limits: Adolescent / Adult / Female / Humans / Male / Middle aged Language: En Journal: Clin Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2017 Document type: Article