What's in an Average? An Ensemble View of Phosphorylation Effects.
Structure
; 25(4): 573-575, 2017 04 04.
Article
in En
| MEDLINE
| ID: mdl-28380337
ABSTRACT
The number of examples of functional post-translational modulation of disordered proteins rapidly grows. In a recent issue of Structure, Jie et al. (2017) show that phosphorylation of dynein intermediate chain alters partner binding but retains its dynamic, disorder character. An ensemble model offers an organizing framework to relate function, conformation, and phosphorylation in disordered and ordered proteins alike.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Proteins
/
Dyneins
Limits:
Humans
Language:
En
Journal:
Structure
Journal subject:
BIOLOGIA MOLECULAR
/
BIOQUIMICA
/
BIOTECNOLOGIA
Year:
2017
Document type:
Article
Affiliation country:
United States