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CYP3A4 genotype is associated with sildenafil concentrations in patients with heart failure with preserved ejection fraction.
de Denus, S; Rouleau, J L; Mann, D L; Huggins, G S; Pereira, N L; Shah, S H; Cappola, T P; Fouodjio, R; Mongrain, I; Dubé, M-P.
Affiliation
  • de Denus S; Research Center, Montreal Heart Institute, Montreal, Quebec, Canada.
  • Rouleau JL; Université de Montréal Beaulieu-Saucier Pharmacogenomics Center, Montreal, Quebec, Canada.
  • Mann DL; Faculty of Pharmacy, University of Montreal, Montreal, Quebec, Canada.
  • Huggins GS; Research Center, Montreal Heart Institute, Montreal, Quebec, Canada.
  • Pereira NL; Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada.
  • Shah SH; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
  • Cappola TP; Molecular Cardiology Research Institute Center for Translational Genomics, Tufts Medical Center, Boston, MA, USA.
  • Fouodjio R; Division of Cardiovascular Diseases, Division of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA.
  • Mongrain I; Division of Cardiology, Duke University School of Medicine, Durham, NC, USA.
  • Dubé MP; Division of Cardiovascular Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Pharmacogenomics J ; 18(2): 232-237, 2018 04.
Article in En | MEDLINE | ID: mdl-28440343
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stroke Volume / Vasodilator Agents / Cytochrome P-450 CYP3A / Sildenafil Citrate / Genotype / Heart Failure Type of study: Clinical_trials / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Pharmacogenomics J Journal subject: BIOLOGIA MOLECULAR / FARMACOLOGIA Year: 2018 Document type: Article Affiliation country: Canada
Fulltext
Add to My VHL
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XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stroke Volume / Vasodilator Agents / Cytochrome P-450 CYP3A / Sildenafil Citrate / Genotype / Heart Failure Type of study: Clinical_trials / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Pharmacogenomics J Journal subject: BIOLOGIA MOLECULAR / FARMACOLOGIA Year: 2018 Document type: Article Affiliation country: Canada