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Addressing unmet needs in understanding asthma mechanisms: From the European Asthma Research and Innovation Partnership (EARIP) Work Package (WP)2 collaborators.
Edwards, Michael R; Saglani, Sejal; Schwarze, Jurgen; Skevaki, Chrysanthi; Smith, Jaclyn A; Ainsworth, Ben; Almond, Mark; Andreakos, Evangelos; Belvisi, Maria G; Chung, Kian Fan; Cookson, William; Cullinan, Paul; Hawrylowicz, Catherine; Lommatzsch, Marek; Jackson, David; Lutter, Rene; Marsland, Benjamin; Moffatt, Miriam; Thomas, Mike; Virchow, J Christian; Xanthou, Georgina; Edwards, Jessica; Walker, Samantha; Johnston, Sebastian L.
Affiliation
  • Edwards MR; Imperial College London, London, UK.
  • Saglani S; Imperial College London, London, UK.
  • Schwarze J; University of Edinburgh, Edinburgh, UK.
  • Skevaki C; Phillips University Marburg, Marburg, Germany.
  • Smith JA; University of Manchester, Manchester, UK.
  • Ainsworth B; University of Southampton, Southampton, UK.
  • Almond M; Imperial College London, London, UK.
  • Andreakos E; Biomedical Research Foundation, Academy of Athens, Athens, Greece.
  • Belvisi MG; Imperial College London, London, UK.
  • Chung KF; Imperial College London, London, UK.
  • Cookson W; Imperial College London, London, UK.
  • Cullinan P; Imperial College London, London, UK.
  • Hawrylowicz C; Kings College London, London, UK.
  • Lommatzsch M; University of Rostock, Rostock, Germany.
  • Jackson D; Imperial College London, London, UK.
  • Lutter R; Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
  • Marsland B; University of Lausanne, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
  • Moffatt M; Imperial College London, London, UK.
  • Thomas M; University of Southampton, Southampton, UK.
  • Virchow JC; University of Rostock, Rostock, Germany.
  • Xanthou G; Biomedical Research Foundation, Academy of Athens, Athens, Greece.
  • Edwards J; Asthma UK, London, UK.
  • Walker S; Asthma UK, London, UK.
  • Johnston SL; Imperial College London, London, UK s.johnston@imperial.ac.uk.
Eur Respir J ; 49(5)2017 05.
Article in En | MEDLINE | ID: mdl-28461300
ABSTRACT
Asthma is a heterogeneous, complex disease with clinical phenotypes that incorporate persistent symptoms and acute exacerbations. It affects many millions of Europeans throughout their education and working lives and puts a heavy cost on European productivity. There is a wide spectrum of disease severity and control. Therapeutic advances have been slow despite greater understanding of basic mechanisms and the lack of satisfactory preventative and disease modifying management for asthma constitutes a significant unmet clinical need. Preventing, treating and ultimately curing asthma requires co-ordinated research and innovation across Europe. The European Asthma Research and Innovation Partnership (EARIP) is an FP7-funded programme which has taken a co-ordinated and integrated approach to analysing the future of asthma research and development. This report aims to identify the mechanistic areas in which investment is required to bring about significant improvements in asthma outcomes.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Asthma / Disease Progression / Needs Assessment / Biomedical Research Type of study: Guideline Limits: Humans Country/Region as subject: Europa Language: En Journal: Eur Respir J Year: 2017 Document type: Article Affiliation country: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Asthma / Disease Progression / Needs Assessment / Biomedical Research Type of study: Guideline Limits: Humans Country/Region as subject: Europa Language: En Journal: Eur Respir J Year: 2017 Document type: Article Affiliation country: United kingdom