Targeting Insulin Receptor in Breast Cancer Using Small Engineered Protein Scaffolds.

Chan, Jie Ying; Hackel, Benjamin J; Yee, Douglas

Chan, Jie Ying; Hackel, Benjamin J; Yee, Douglas.

Affiliation

Chan JY; Department of Pharmacology, University of Minnesota, Minneapolis, Minnesota.
Hackel BJ; Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, Minnesota.
Yee D; Department of Pharmacology, University of Minnesota, Minneapolis, Minnesota. yeexx006@umn.edu.

Mol Cancer Ther ; 16(7): 1324-1334, 2017 07.

Article in En | MEDLINE | ID: mdl-28468775

Subject(s)

Antigens, CD/genetics; Breast Neoplasms/drug therapy; Receptor, Insulin/genetics; Receptors, Somatomedin/genetics; Repressor Proteins/administration & dosage; Animals; Breast Neoplasms/genetics; Breast Neoplasms/pathology; Cell Proliferation/drug effects; Humans; Insulin-Like Growth Factor I/genetics; Insulin-Like Growth Factor II/drug effects; Mice; Nuclear Matrix-Associated Proteins/administration & dosage; Nuclear Matrix-Associated Proteins/genetics; Protein Binding; Receptor, IGF Type 1; Receptor, Insulin/antagonists & inhibitors; Receptors, Somatomedin/antagonists & inhibitors; Repressor Proteins/genetics; Signal Transduction/drug effects; Xenograft Model Antitumor Assays

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Repressor Proteins / Breast Neoplasms / Receptor, Insulin / Antigens, CD / Receptors, Somatomedin Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Mol Cancer Ther Journal subject: ANTINEOPLASICOS Year: 2017 Document type: Article

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google