Diglycosidic indole alkaloid derivatives from an aqueous extract of Isatis indigotica roots.
J Asian Nat Prod Res
; 19(6): 529-540, 2017 Jun.
Article
in En
| MEDLINE
| ID: mdl-28475367
ABSTRACT
Six new indole alkaloid diglycosides named isatigotindolediosides A-F (1-6), along with three known analogs (7-9), were isolated from an aqueous extract of the Isatis indigotica roots (ban lan gen). Their structures including the absolute configurations were determined by comprehensive spectroscopic data analysis, combined with enzyme or acid hydrolysis, and comparison of experimental circular dichroism (CD) and calculated electronic circular dichroism (ECD) spectra. In the preliminary assays, compounds 3, 5, and 8 showed antiviral activity against Coxsackie virus B3.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Plant Roots
/
Indole Alkaloids
/
Isatis
/
Glycosides
Language:
En
Journal:
J Asian Nat Prod Res
Journal subject:
BOTANICA
/
QUIMICA
Year:
2017
Document type:
Article
Affiliation country:
China