Spontaneous regression of methotrexate-related diffuse large B-cell lymphoma following bladder lesion resection.
Rinsho Ketsueki
; 58(4): 287-291, 2017.
Article
in Ja
| MEDLINE
| ID: mdl-28484154
ABSTRACT
A 71-year-old woman who had been treated with methotrexate (MTX) and prednisolone for rheumatoid arthritis since 2010 presented with hematuria. Cystitis was diagnosed. Chest and abdominal CT images revealed a bladder tumor, with lung and bilateral adrenal metastases. Transurethral resection of the bladder tumor (TUR-BT) confirmed these findings in September 2014. Histological findings of the bladder included large atypical lymphoid cells indicating diffuse large B-cell lymphoma. After TUR-BT, CT imaging showed that the tumor had shrunk. Still, MTX was continued. She was diagnosed with MTX-related lymphoproliferative disorders in November 2014 and MTX was discontinued. Fluorodeoxyglucose-positron emission tomography on March 2015 showed a complete response.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Urinary Bladder
/
Urinary Bladder Neoplasms
/
Lymphoma, Large B-Cell, Diffuse
/
Antirheumatic Agents
/
Neoplasm Regression, Spontaneous
Limits:
Aged
/
Female
/
Humans
Language:
Ja
Journal:
Rinsho Ketsueki
Year:
2017
Document type:
Article