Rapid Detection of Small Molecule Metabolites in Serum of Hepatocellular Carcinoma Patients Using Ultrafast Liquid Chromatography-Ion Trap-Time of Flight Tandem Mass Spectrometry.

Li, Hui; Fan, Su-Fang; Wang, Yan; Shen, Shi-Gang; Sun, Dian-Xing

Li, Hui; Fan, Su-Fang; Wang, Yan; Shen, Shi-Gang; Sun, Dian-Xing.

Affiliation

Li H; The Liver Disease Diagnosis and Treatment Center of PLA, Bethune International Peace Hospital.
Fan SF; Hebei Food Safety Key Laboratory, Hebei Food Inspection and Research Institute.
Wang Y; Hebei Food Safety Key Laboratory, Hebei Food Inspection and Research Institute.
Shen SG; The Liver Disease Diagnosis and Treatment Center of PLA, Bethune International Peace Hospital.
Sun DX; Key Laboratory of Analytical Science and Technology of Hebei Province.

Anal Sci ; 33(5): 573-578, 2017.

Article in En | MEDLINE | ID: mdl-28496060

Subject(s)

Carcinoma, Hepatocellular/chemistry; Small Molecule Libraries/metabolism; Acetylcarnitine/analysis; Acetylcarnitine/metabolism; Amides/analysis; Amides/metabolism; Carcinoma, Hepatocellular/metabolism; Chromatography, High Pressure Liquid; Glycerylphosphorylcholine/analysis; Glycerylphosphorylcholine/metabolism; Glycochenodeoxycholic Acid/analysis; Glycochenodeoxycholic Acid/metabolism; Glycocholic Acid/analysis; Glycocholic Acid/metabolism; Humans; Lysophosphatidylcholines/analysis; Lysophosphatidylcholines/metabolism; Oleic Acids/analysis; Oleic Acids/metabolism; Phenylalanine/analysis; Phenylalanine/metabolism; Small Molecule Libraries/analysis; Tandem Mass Spectrometry

Key words

UFLC-IT-TOF MS; hepatocellular carcinoma; metabonomics; serum

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Hepatocellular / Small Molecule Libraries Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Anal Sci Year: 2017 Document type: Article

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