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Advanced multivariate data analysis to determine the root cause of trisulfide bond formation in a novel antibody-peptide fusion.
Goldrick, Stephen; Holmes, William; Bond, Nicholas J; Lewis, Gareth; Kuiper, Marcel; Turner, Richard; Farid, Suzanne S.
Affiliation
  • Goldrick S; Department of Biochemical Engineering, The Advanced Centre of Biochemical Engineering, University College London, Gordon Street, WC1H 0AH London, United Kingdom.
  • Holmes W; MedImmune, Granta Park, Cambridge CB21 6GH, United Kingdom.
  • Bond NJ; MedImmune, Granta Park, Cambridge CB21 6GH, United Kingdom.
  • Lewis G; MedImmune, Granta Park, Cambridge CB21 6GH, United Kingdom.
  • Kuiper M; MedImmune, Granta Park, Cambridge CB21 6GH, United Kingdom.
  • Turner R; MedImmune, Granta Park, Cambridge CB21 6GH, United Kingdom.
  • Farid SS; MedImmune, Granta Park, Cambridge CB21 6GH, United Kingdom.
Biotechnol Bioeng ; 114(10): 2222-2234, 2017 10.
Article in En | MEDLINE | ID: mdl-28500668
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Sulfides / Recombinant Fusion Proteins / Multivariate Analysis / Protein Interaction Mapping / Antibodies, Monoclonal Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Biotechnol Bioeng Year: 2017 Document type: Article Affiliation country: United kingdom Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Sulfides / Recombinant Fusion Proteins / Multivariate Analysis / Protein Interaction Mapping / Antibodies, Monoclonal Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Biotechnol Bioeng Year: 2017 Document type: Article Affiliation country: United kingdom Country of publication: United States