Pinpointing disulfide connectivities in cysteine-rich proteins.
Chem Commun (Camb)
; 53(53): 7337-7340, 2017 Jun 29.
Article
in En
| MEDLINE
| ID: mdl-28508909
ABSTRACT
A simple MD-based protocol is presented to accurately predict both the sequence and order of disulfide bond formation in proteins containing multiple cysteine residues. It provides a detailed description of their dynamical and structural features, which can be used to perform ensemble-averaged ECD calculations. Plant cyclotides are used as model compounds.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cysteine
/
Cyclotides
/
Disulfides
Type of study:
Prognostic_studies
Language:
En
Journal:
Chem Commun (Camb)
Journal subject:
QUIMICA
Year:
2017
Document type:
Article
Affiliation country:
Brazil
Publication country:
ENGLAND
/
ESCOCIA
/
GB
/
GREAT BRITAIN
/
INGLATERRA
/
REINO UNIDO
/
SCOTLAND
/
UK
/
UNITED KINGDOM