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The distinct metabolic phenotype of lung squamous cell carcinoma defines selective vulnerability to glycolytic inhibition.
Goodwin, Justin; Neugent, Michael L; Lee, Shin Yup; Choe, Joshua H; Choi, Hyunsung; Jenkins, Dana M R; Ruthenborg, Robin J; Robinson, Maddox W; Jeong, Ji Yun; Wake, Masaki; Abe, Hajime; Takeda, Norihiko; Endo, Hiroko; Inoue, Masahiro; Xuan, Zhenyu; Yoo, Hyuntae; Chen, Min; Ahn, Jung-Mo; Minna, John D; Helke, Kristi L; Singh, Pankaj K; Shackelford, David B; Kim, Jung-Whan.
Affiliation
  • Goodwin J; Department of Biological Sciences, The University of Texas at Dallas, Richardson, Texas 75080, USA.
  • Neugent ML; Department of Biological Sciences, The University of Texas at Dallas, Richardson, Texas 75080, USA.
  • Lee SY; Department of Biological Sciences, The University of Texas at Dallas, Richardson, Texas 75080, USA.
  • Choe JH; Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu 41944, Korea.
  • Choi H; Department of Biological Sciences, The University of Texas at Dallas, Richardson, Texas 75080, USA.
  • Jenkins DMR; St Mark's School of Texas, Dallas, Texas 75230, USA.
  • Ruthenborg RJ; Department of Biological Sciences, The University of Texas at Dallas, Richardson, Texas 75080, USA.
  • Robinson MW; Department of Biological Sciences, The University of Texas at Dallas, Richardson, Texas 75080, USA.
  • Jeong JY; Department of Biological Sciences, The University of Texas at Dallas, Richardson, Texas 75080, USA.
  • Wake M; Department of Biological Sciences, The University of Texas at Dallas, Richardson, Texas 75080, USA.
  • Abe H; Department of Pathology, School of Medicine, Kyungpook National University, Daegu 41944, Korea.
  • Takeda N; Department of Cardiovascular Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
  • Endo H; Department of Cardiovascular Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
  • Inoue M; Department of Cardiovascular Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
  • Xuan Z; Department of Biochemistry, Osaka International Cancer Institute, Osaka 541-8567, Japan.
  • Yoo H; Department of Biochemistry, Osaka International Cancer Institute, Osaka 541-8567, Japan.
  • Chen M; Department of Biological Sciences, The University of Texas at Dallas, Richardson, Texas 75080, USA.
  • Ahn JM; The Center for Systems Biology, The University of Texas at Dallas, Richardson, Texas 75080, USA.
  • Minna JD; Department of Biological Sciences, The University of Texas at Dallas, Richardson, Texas 75080, USA.
  • Helke KL; Department of Mathematical Sciences, The University of Texas at Dallas, Richardson, Texas 75080, USA.
  • Singh PK; Department of Chemistry and Biochemistry, The University of Texas at Dallas, Richardson, Texas 75080, USA.
  • Shackelford DB; Department of Medicine and Pharmacology, Hamon Center for Therapeutic Oncology Research, Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Nat Commun ; 8: 15503, 2017 05 26.
Article in En | MEDLINE | ID: mdl-28548087
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Squamous Cell / Adenocarcinoma / Carcinoma, Non-Small-Cell Lung / Glucose / Lung Neoplasms Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies Limits: Aged80 Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2017 Document type: Article Affiliation country: United States Country of publication: United kingdom
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Squamous Cell / Adenocarcinoma / Carcinoma, Non-Small-Cell Lung / Glucose / Lung Neoplasms Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies Limits: Aged80 Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2017 Document type: Article Affiliation country: United States Country of publication: United kingdom