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Immuno-nephelometric determination of group streptococcal anti-streptolysin O titres (ASOT) from dried blood spots: Method for validating a new assay.
Joseph, John; Kent, Neil; Bowen, Asha; Hart, Julie; Sheel, Meru; Wardrop, Robert; Abbs, Sam; Bazely, Scott; Rybak, Monika.
Affiliation
  • Joseph J; PathWest Laboratory Medicine, QE2 Medical Centre Redevelopment, Australia. Electronic address: john.joseph@health.wa.gov.au.
  • Kent N; PathWest Laboratory Medicine, QE2 Medical Centre Redevelopment, Australia.
  • Bowen A; Menzies School of Health Research, Charles Darwin University, Australia; Wesfarmers Centre for Vaccines and Infectious Diseases, Telethon Kids Institute, University of Western Australia, Australia; Princess Margaret Hospital for Children, Australia; University of Western Australia, Australia.
  • Hart J; PathWest Laboratory Medicine, QE2 Medical Centre Redevelopment, Australia.
  • Sheel M; Wesfarmers Centre for Vaccines and Infectious Diseases, Telethon Kids Institute, University of Western Australia, Australia.
  • Wardrop R; Gilbert Bain Hospital NHS Shetland, UK.
  • Abbs S; PathWest Laboratory Medicine, QE2 Medical Centre Redevelopment, Australia.
  • Bazely S; University of Western Australia, Australia.
  • Rybak M; PathWest Laboratory Medicine, QE2 Medical Centre Redevelopment, Australia.
J Immunol Methods ; 448: 59-65, 2017 09.
Article in En | MEDLINE | ID: mdl-28554544
This study was designed to determine the sensitivity and reproducibility of recovering anti-streptolysin O titres (ASOT) from dried blood spot (DBS) samples, a methodologic subcomponent of the penicillin pharmacokinetic studies in children receiving secondary prophylaxis with intramuscular benzathine penicillin for acute rheumatic fever.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rheumatic Fever / Streptolysins / Immunologic Tests / Dried Blood Spot Testing / Antistreptolysin Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: J Immunol Methods Year: 2017 Document type: Article Country of publication: Netherlands
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rheumatic Fever / Streptolysins / Immunologic Tests / Dried Blood Spot Testing / Antistreptolysin Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: J Immunol Methods Year: 2017 Document type: Article Country of publication: Netherlands