Repeated surgeries in invasive lobular breast cancer with preoperative MRI: Role of additional carcinoma in situ and background parenchymal enhancement.
Eur J Radiol
; 90: 181-187, 2017 May.
Article
in En
| MEDLINE
| ID: mdl-28583631
ABSTRACT
OBJECTIVES:
Analysing the influence of additional carcinoma in situ (CIS) and background parenchymal enhancement (BPE) in preoperative MRI on repeated surgeries in patients with invasive lobular carcinoma (ILC) of the breast.METHODS:
Retrospective analysis of 106 patients (mean age 58.6±9.9years) with 108 ILC. Preoperative tumour size as assessed by MRI, mammography and sonography was recorded and compared to histopathology. In contrast-enhanced MRI, the degree of BPE was categorised by two readers. The influence of additionally detected CIS and BPE on the rate of repeated surgeries was analysed.RESULTS:
Additional CIS was present in 45.4% of the cases (49/108). The degree of BPE was minimal or mild in 80% of the cases and moderate or marked in 20% of the cases. In 17 cases (15.7%) at least one repeated surgery was performed. In n=15 of these cases, repeated surgery was performed after BCT (n=9 re-excisions, n=6 conversions to mastectomy), in n=2 cases after initial mastectomy. The initial surgical procedure (p=0.008) and additional CIS (p=0.046) significantly influenced the rate of repeated surgeries, while tumour size, patient age and BPE did not (p=ns).CONCLUSIONS:
Additional CIS was associated with a higher rate of repeated surgeries, whereas BPE had no influence.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Reoperation
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Breast Neoplasms
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Preoperative Care
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Magnetic Resonance Imaging
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Carcinoma in Situ
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Carcinoma, Lobular
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Parenchymal Tissue
Type of study:
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
Limits:
Adult
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Aged
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Aged80
/
Female
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Humans
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Middle aged
Language:
En
Journal:
Eur J Radiol
Year:
2017
Document type:
Article