Comprehensive Cross-Clade Characterization of Antibody-Mediated Recognition, Complement-Mediated Lysis, and Cell-Mediated Cytotoxicity of HIV-1 Envelope-Specific Antibodies toward Eradication of the HIV-1 Reservoir.

Mujib, Shariq; Liu, Jun; Rahman, A K M Nur-Ur; Schwartz, Jordan A; Bonner, Phil; Yue, Feng Yun; Ostrowski, Mario A

Mujib, Shariq; Liu, Jun; Rahman, A K M Nur-Ur; Schwartz, Jordan A; Bonner, Phil; Yue, Feng Yun; Ostrowski, Mario A.

Affiliation

Mujib S; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.
Liu J; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
Rahman AKMN; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
Schwartz JA; Department of Immunology, University of Toronto, Toronto, Ontario, Canada.
Bonner P; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
Yue FY; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
Ostrowski MA; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada mario.ostrowski@gmail.com.

J Virol ; 91(16)2017 08 15.

Article in En | MEDLINE | ID: mdl-28592534

Subject(s)

Antibodies, Neutralizing/immunology; Antibody-Dependent Cell Cytotoxicity; Complement System Proteins/immunology; Cross Reactions; HIV Antibodies/immunology; HIV-1/immunology; Humans

Key words

ADCC; ADCML; AIDS; antibody function; complement-mediated lysis; human immunodeficiency virus; monoclonal antibodies; neutralizing antibodies

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Complement System Proteins / HIV Antibodies / HIV-1 / Cross Reactions / Antibodies, Neutralizing / Antibody-Dependent Cell Cytotoxicity Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Virol Year: 2017 Document type: Article Affiliation country: Canada Country of publication: United States

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