Architecture of the paracellular channels formed by claudins of the blood-brain barrier tight junctions.

Irudayanathan, Flaviyan Jerome; Wang, Nan; Wang, Xiaoyi; Nangia, Shikha

Irudayanathan, Flaviyan Jerome; Wang, Nan; Wang, Xiaoyi; Nangia, Shikha.

Affiliation

Irudayanathan FJ; Department of Biomedical and Chemical Engineering, Syracuse University, Syracuse, New York.
Wang N; Department of Biomedical and Chemical Engineering, Syracuse University, Syracuse, New York.
Wang X; Department of Biomedical and Chemical Engineering, Syracuse University, Syracuse, New York.
Nangia S; Department of Biomedical and Chemical Engineering, Syracuse University, Syracuse, New York.

Ann N Y Acad Sci ; 1405(1): 131-146, 2017 10.

Article in En | MEDLINE | ID: mdl-28614588

Subject(s)

Blood-Brain Barrier/metabolism; Claudins/metabolism; Molecular Dynamics Simulation; Tight Junctions/metabolism; Animals; Biological Transport; Molecular Docking Simulation

Key words

cis-interactions; claudin; dimer; paracellular transport; pore structure; tight junctions

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood-Brain Barrier / Tight Junctions / Claudins / Molecular Dynamics Simulation Limits: Animals Language: En Journal: Ann N Y Acad Sci Year: 2017 Document type: Article Country of publication: United States

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