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A phase Ib trial of continuous once-daily oral afatinib plus sirolimus in patients with epidermal growth factor receptor mutation-positive non-small cell lung cancer and/or disease progression following prior erlotinib or gefitinib.
Moran, Teresa; Palmero, Ramón; Provencio, Mariano; Insa, Amelia; Majem, Margarita; Reguart, Noemí; Bosch-Barrera, Joaquim; Isla, Dolores; Costa, Enric Carcereny; Lee, Chooi; Puig, Marta; Kraemer, Sandrine; Schnell, David; Rosell, Rafael.
Affiliation
  • Moran T; Medical Oncology Department, Catalan Institute of Oncology-Badalona, Hospital Germans Trias i Pujol, Badalona, Universitat Autònoma de Barcelona (UAB), Carretera de Canyet s/n, 08916 Badalona, Barcelona, Spain. Electronic address: mmoran@iconcologia.net.
  • Palmero R; Medical Oncology Department, Catalan Institute of Oncology, Hospital Duran i Reynals, Barcelona, Spain. Electronic address: rpalmero@iconcologia.net.
  • Provencio M; Medical Oncology Department, Hospital Puerta de Hierro, Medicine Autonomous University of Madrid, Spain. Electronic address: mprovenciop@gmail.com.
  • Insa A; Medical Oncology Department, Hospital Clinico Universitario de Valencia, Valencia, Spain. Electronic address: amelia_insa@ono.com.
  • Majem M; Medical Oncology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain. Electronic address: MMajem@santpau.cat.
  • Reguart N; Medical Oncology Department, Hospital Clinic ICMHO, Barcelona, Spain. Electronic address: nreguart@clinic.ub.es.
  • Bosch-Barrera J; Medical Oncology Department, Catalan Institute of Oncology, Hospital Dr. Josep Trueta, Girona, Spain. Electronic address: jbosch@iconcologia.net.
  • Isla D; Medical Oncology Department, Hospital Lozano Blesa, University Hospital Lozano Blesa, Avda. S. Juan Bosco nº 15, 50009, Zaragoza, Spain. Electronic address: lola.isla@gmail.com.
  • Costa EC; Medical Oncology Department, Catalan Institute of Oncology-Badalona, Hospital Germans Trias i Pujol, Badalona, Universitat Autònoma de Barcelona (UAB), Carretera de Canyet s/n, 08916 Badalona, Barcelona, Spain. Electronic address: ecarcereny@iconcologia.net.
  • Lee C; Boehringer Ingelheim Ltd., Bracknell, Berkshire, UK. Electronic address: chooi.lee@boehringer-ingelheim.com.
  • Puig M; Clinical Research-Oncology, Medical Department R&D, Boehringer Ingelheim S.A., Sant Cugat del Vallès, Spain. Electronic address: marta.puig@boehringer-ingelheim.com.
  • Kraemer S; Boehringer Ingelheim, Reims, France. Electronic address: sandrine.kraemer@boehringer-ingelheim.com.
  • Schnell D; Translational Medicine and Clinical Pharmacology, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany. Electronic address: david.schnell.ext@boehringer-ingelheim.com.
  • Rosell R; Cancer Biology & Precision Medicine Program, Catalan Institute of Oncology, Germans Trias i Pujol Health Sciences Institute and Hospital, Badalona, Spain; Dr. Rosell Oncology Institute, Quirón Dexeus University Hospital, Barcelona, Spain; Molecular Oncology Research Foundation (MORe), Barcelona,
Lung Cancer ; 108: 154-160, 2017 06.
Article in En | MEDLINE | ID: mdl-28625629
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antineoplastic Combined Chemotherapy Protocols / Carcinoma, Non-Small-Cell Lung / ErbB Receptors / Lung Neoplasms / Mutation Type of study: Clinical_trials / Prognostic_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Lung Cancer Journal subject: NEOPLASIAS Year: 2017 Document type: Article Country of publication: Ireland
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antineoplastic Combined Chemotherapy Protocols / Carcinoma, Non-Small-Cell Lung / ErbB Receptors / Lung Neoplasms / Mutation Type of study: Clinical_trials / Prognostic_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Lung Cancer Journal subject: NEOPLASIAS Year: 2017 Document type: Article Country of publication: Ireland