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Nuclear import of glucokinase in pancreatic beta-cells is mediated by a nuclear localization signal and modulated by SUMOylation.
Johansson, Bente Berg; Fjeld, Karianne; Solheim, Marie Holm; Shirakawa, Jun; Zhang, Enming; Keindl, Magdalena; Hu, Jiang; Lindqvist, Andreas; Døskeland, Anne; Mellgren, Gunnar; Flatmark, Torgeir; Njølstad, Pål Rasmus; Kulkarni, Rohit N; Wierup, Nils; Aukrust, Ingvild; Bjørkhaug, Lise.
Affiliation
  • Johansson BB; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Norway; Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway; Department of Pediatrics, Haukeland University Hospital, Bergen, Norway.
  • Fjeld K; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Norway; Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway.
  • Solheim MH; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Norway; Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center and Harvard Medical School
  • Shirakawa J; Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School and Harvard Stem Cell Institute, Boston, MA, USA; Department of Endocrinology and Metabolism, Yokohama City University, Yokohama, Japan.
  • Zhang E; Lund University Diabetes Centre, Malmö, Sweden.
  • Keindl M; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Norway; Hormone Laboratory, Haukeland University Hospital, Bergen, Norway.
  • Hu J; Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School and Harvard Stem Cell Institute, Boston, MA, USA.
  • Lindqvist A; Lund University Diabetes Centre, Malmö, Sweden.
  • Døskeland A; Proteomics Unit (PROBE), Department of Biomedicine, University of Bergen, Norway.
  • Mellgren G; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Norway; Hormone Laboratory, Haukeland University Hospital, Bergen, Norway; Department of Clinical Science, University of Bergen, Bergen, Norway.
  • Flatmark T; Department of Biomedicine, University of Bergen, Bergen, Norway.
  • Njølstad PR; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Norway; Department of Pediatrics, Haukeland University Hospital, Bergen, Norway.
  • Kulkarni RN; Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School and Harvard Stem Cell Institute, Boston, MA, USA.
  • Wierup N; Lund University Diabetes Centre, Malmö, Sweden.
  • Aukrust I; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Norway; Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway.
  • Bjørkhaug L; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Norway; Department of Biomedicine, University of Bergen, Bergen, Norway; Department of Biomedical Laboratory Sciences and Chemical Engineering, Western Norway University of Applied Sciences, Bergen, Norway.
Mol Cell Endocrinol ; 454: 146-157, 2017 10 15.
Article in En | MEDLINE | ID: mdl-28648619
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Nucleus / Nuclear Localization Signals / Insulin-Secreting Cells / Sumoylation / Glucokinase Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Mol Cell Endocrinol Year: 2017 Document type: Article Affiliation country: Norway Country of publication: Ireland
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Nucleus / Nuclear Localization Signals / Insulin-Secreting Cells / Sumoylation / Glucokinase Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Mol Cell Endocrinol Year: 2017 Document type: Article Affiliation country: Norway Country of publication: Ireland