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Dual targeting of Bruton tyrosine kinase and CD52 induces minimal residual disease-negativity in the bone marrow of poor-prognosis chronic lymphocytic leukaemia patients but is associated with opportunistic infections - Results from a phase I study.
Winqvist, Maria; Palma, Marzia; Heimersson, Kia; Mellstedt, Håkan; Österborg, Anders; Lundin, Jeanette.
Affiliation
  • Winqvist M; Department of Hematology, Karolinska University Hospital, Stockholm, Sweden.
  • Palma M; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
  • Heimersson K; Department of Hematology, Karolinska University Hospital, Stockholm, Sweden.
  • Mellstedt H; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
  • Österborg A; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
  • Lundin J; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Br J Haematol ; 182(4): 590-594, 2018 08.
Article in En | MEDLINE | ID: mdl-28677818
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bone Marrow / Opportunistic Infections / Leukemia, Lymphocytic, Chronic, B-Cell / Antineoplastic Combined Chemotherapy Protocols / CD52 Antigen / Agammaglobulinaemia Tyrosine Kinase Type of study: Clinical_trials / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Br J Haematol Year: 2018 Document type: Article Affiliation country: Sweden Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bone Marrow / Opportunistic Infections / Leukemia, Lymphocytic, Chronic, B-Cell / Antineoplastic Combined Chemotherapy Protocols / CD52 Antigen / Agammaglobulinaemia Tyrosine Kinase Type of study: Clinical_trials / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Br J Haematol Year: 2018 Document type: Article Affiliation country: Sweden Country of publication: United kingdom